Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 11/20 | 0.46 |
| ▸ | CRHR1 | P34998 | 8/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787017 | 0.80 | SLC6A9 (0.46) | SLC6A9 | |
| SCHEMBL4193120 | 0.77 | SLC6A9 (0.70) | SLC6A9 | |
| SCHEMBL4177252 | 0.76 | SLC6A9 (0.73) | SLC6A9 | |
| SCHEMBL786978 | 0.75 | SLC6A9 (0.55) | SLC6A9CRHR1ITGB1ITGA4 | |
| SCHEMBL786955 | 0.74 | SLC6A9 (0.66) | SLC6A9 | |
| Hydrochloric Acid SCHEMBL787493 | 0.74 | SLC6A9 (0.54) | SLC6A9CRHR1ITGB1ITGA4 | |
| SCHEMBL4335143 | 0.72 | SLC6A9 (0.51) | SLC6A9 | |
| SCHEMBL786894 | 0.72 | SLC6A9 (0.68) | SLC6A9 | |
| SCHEMBL4193318 | 0.71 | SLC6A9 (0.56) | SLC6A9CRHR1ITGB1ITGA4 | |
| SCHEMBL787071 | 0.71 | SLC6A9 (0.52) | SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071536-A1 | N-[(2-AZABICYCLO[2.1.1]HEX-1-YL)-ARYL-METHYL]-BENZAMIDE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071536-A1 | N-[(2-AZABICYCLO[2.1.1]HEX-1-YL)-ARYL-METHYL]-BENZAMIDE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | HRH4, NT5C, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | SLC6A9 3512/4885CRHR1 275/4885ITGB1 4094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.