Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9351879 | 0.77 | TSHR (0.38) | KDM4EKMT2AL3MBTL1HSD17B10CA1 | |
| SCHEMBL9249596 | 0.72 | NPSR1 (0.47) | KDM4EKMT2ACA1CA2NPSR1 | |
| SCHEMBL11024087 | 0.72 | TSHR (0.43) | KDM4EKMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL605052 | 0.69 | — | — | |
| SCHEMBL17267098 | 0.68 | HSD17B10 (0.43) | KDM4EKMT2AL3MBTL1HSD17B10CA1 | |
| SCHEMBL27261499 | 0.68 | HSD17B10 (0.43) | KDM4EKMT2AL3MBTL1HSD17B10CA1 | |
| SCHEMBL27261501 | 0.68 | HSD17B10 (0.43) | KDM4EKMT2AL3MBTL1HSD17B10CA1 | |
| SCHEMBL17878613 | 0.68 | CYP3A4 (0.45) | L3MBTL1CYP3A4TSHRALDH1A1GAA | |
| SCHEMBL4266923 | 0.68 | TSHR (0.46) | KMT2ACYP3A4CYP2C9CYP2C19CA1 | |
| SCHEMBL5861940 | 0.68 | HSD17B10 (0.41) | KDM4EKMT2AL3MBTL1HSD17B10CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035303-A2 | A NOVEL PROCESS FOR SYNTHESIS OF RAMELTEON, AND KEY INTERMEDIATES FOR THE SYNTHESIS OF RAMELTEON | CIPLA LIMITED ET AL (IN) | 2012-03-22 | — | — | WO | claimed |
| WO-2012035303-A2 | A NOVEL PROCESS FOR SYNTHESIS OF RAMELTEON, AND KEY INTERMEDIATES FOR THE SYNTHESIS OF RAMELTEON | CIPLA LIMITED ET AL (IN) | 2012-03-22 | — | — | WO | disclosed |