Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL787514

O=C(O)C(F)(F)F.O=C1CNCc2ccc(F)cc2N1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR5A P47898 2/20 0.36
DPP4 P27487 2/20 0.36
KDM1A O60341 1/20 0.36
CMA1 P23946 1/20 0.36
AHR P35869 1/20 0.36
TRPV1 Q8NER1 1/20 0.35
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HDAC3 O15379 1/20 0.34
MAPT P10636 1/20 0.34
SRD5A1 P18405 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8031052 0.88 HTR5A (0.44) HTR5ACMA1AHRKMT2AMEN1
Trifluoroacetic Acid SCHEMBL3430565 0.81 AHR (0.46) HTR5AKDM1AAHRKMT2AMEN1
SCHEMBL8018199 0.76 HTR5A (0.44) HTR5AAHRKMT2AMEN1NPC1
SCHEMBL20895861 0.75 HTT (0.51) CMA1AHRKDM4ESMN1; SMN2MAPT
SCHEMBL30015960 0.71 CMA1 (0.68) CMA1AHRKMT2AMEN1
SCHEMBL29134878 0.71 CMA1 (0.68) CMA1AHRKMT2AMEN1
SCHEMBL260027 0.70 AHR (0.61) HTR5ACMA1AHRKMT2AMEN1
SCHEMBL30648196 0.70 AHR (0.61) HTR5ACMA1AHRKMT2AMEN1
SCHEMBL15424346 0.69 CA9 (0.64) CMA1AHRKMT2AMEN1KDM4E
SCHEMBL13002462 0.69 MMP12 (0.47) HTR5ACMA1AHRKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012035549-A2 AN IMPROVED PROCESS FOR THE SYNTHESIS OF BETA AMINO ACID DERIVATIVES PANACEA BIOTEC LTD (IN) 2012-03-22 WO disclosed