Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 10/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877317 | 0.82 | PKM (0.56) | TBXAS1GAAMEN1KMT2APOLB | |
| SCHEMBL7877344 | 0.80 | TBXAS1 (0.53) | TBXAS1ALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL7873758 | 0.80 | TBXAS1 (0.56) | TBXAS1ALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL7868705 | 0.78 | MEN1 (0.50) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL12045307 | 0.73 | TBXAS1 (0.82) | TBXAS1ALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL14255015 | 0.73 | TBXAS1 (0.66) | TBXAS1ALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL14255017 | 0.73 | TBXAS1 (0.66) | TBXAS1ALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL10848211 | 0.73 | PKM (0.79) | ALDH1A1GAASMN1; SMN2POLBPKM | |
| SCHEMBL8447429 | 0.73 | SMN1; SMN2 (0.53) | TBXAS1ALDH1A1SMN1; SMN2PKMLMNA | |
| SCHEMBL10476929 | 0.72 | TBXAS1 (0.79) | TBXAS1ALDH1A1KDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326500-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | ABBOTT LABORATORIES | 2001-12-04 | — | — | US | disclosed |
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| US-5780642-A | NON-STEROIDAL ANTIINFLAMMATORY AGENT WHICH BLOCKS RELEASE OF ARACHIDONIC ACID FROM PHOSPHOLIPIDS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |