Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.47 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.47 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.47 |
| ▸ | P4HB | P07237 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7871441 | 0.88 | FGFR1 (0.64) | FGFR1HTT | |
| SCHEMBL17336856 | 0.79 | PTPN1 (0.47) | HPGDKMT2AHTT | |
| SCHEMBL5869170 | 0.78 | LMNA (0.45) | KMT2A | |
| SCHEMBL7382130 | 0.77 | FGFR1 (0.72) | FGFR1HTT | |
| SCHEMBL1354830 | 0.76 | FGFR1 (0.71) | FGFR1HPGDHTT | |
| SCHEMBL29993296 | 0.76 | FGFR1 (0.72) | FGFR1P4HBHTT | |
| SCHEMBL22583692 | 0.76 | FGFR1 (0.72) | FGFR1P4HBHTT | |
| SCHEMBL29526516 | 0.76 | FGFR1 (0.71) | FGFR1HPGDHTT | |
| SCHEMBL9261352 | 0.76 | FGFR1 (0.74) | FGFR1HPGDHTT | |
| SCHEMBL14668363 | 0.75 | HTT (0.58) | FGFR1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306853-B1 | DICARBOXYLIC ESTER DERIVATIVES OF DIHYDROPYRIDINE COMPOUNDS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-10-23 | — | — | US | disclosed |
| EP-1055672-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 2000-11-29 | — | — | EP | disclosed |