Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131912 | 0.85 | GPR35 (0.56) | GPR35ALDH1A1TSHRHPGDMAPK1 | |
| SCHEMBL83798 | 0.85 | GPR35 (0.60) | GPR35ALDH1A1TSHRHPGDMAPK1 | |
| SCHEMBL1531285 | 0.83 | GPR35 (0.58) | GPR35ALDH1A1TSHRHPGDMAPK1 | |
| SCHEMBL1091651 | 0.83 | GPR35 (0.58) | GPR35ALDH1A1TSHRHPGDMAPK1 | |
| SCHEMBL24407450 | 0.83 | GPR35 (0.50) | GPR35ALDH1A1TSHRHPGDMAPK1 | |
| SCHEMBL260864 | 0.82 | CYP1A2 (0.47) | GPR35ALDH1A1TSHRHPGDMAPK1 | |
| SCHEMBL29368452 | 0.82 | CYP1A2 (0.47) | GPR35ALDH1A1TSHRHPGDMAPK1 | |
| SCHEMBL260847 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRSMN1; SMN2GAACYP1A2 | |
| SCHEMBL6691566 | 0.81 | GPR35 (0.56) | GPR35ALDH1A1TSHRHPGDMAPK1 | |
| SCHEMBL29617011 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRSMN1; SMN2GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326179-B1 | ENZYMATIC IMMUNOGLOBULIN; FOR USE AS THERAPEUTIC AND DIAGNOSTIC TOOLS IN TREATMENT OF ARTHRITIS, VIRAL DISEASE AND ALZHEIMER'S DISEASE | Koentgen, Frank (AU) | 2001-12-04 | — | — | US | disclosed |