Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 3/20 | 0.47 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.47 |
| ▸ | RXRA | P19793 | 13/20 | 0.44 |
| ▸ | RXRB | P28702 | 9/20 | 0.44 |
| ▸ | RXRG | P48443 | 8/20 | 0.44 |
| ▸ | RARA | P10276 | 4/20 | 0.44 |
| ▸ | RARB | P10826 | 4/20 | 0.44 |
| ▸ | RARG | P13631 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7876465 | 1.00 | CYP26A1 (0.47) | CYP26A1CYP26B1RXRARXRBRXRG | |
| SCHEMBL7872162 | 0.89 | CYP26A1 (0.51) | CYP26A1CYP26B1RXRARXRBRXRG | |
| SCHEMBL7872160 | 0.89 | CYP26A1 (0.51) | CYP26A1CYP26B1RXRARXRBRXRG | |
| SCHEMBL7872241 | 0.86 | RARB (0.50) | CYP26A1CYP26B1RXRARXRBRXRG | |
| SCHEMBL7872239 | 0.86 | RARB (0.50) | CYP26A1CYP26B1RXRARXRBRXRG | |
| SCHEMBL7872275 | 0.80 | CYP26A1 (0.51) | CYP26A1CYP26B1RXRARXRBRXRG | |
| SCHEMBL7872280 | 0.80 | CYP26A1 (0.51) | CYP26A1CYP26B1RXRARXRBRXRG | |
| SCHEMBL8189493 | 0.78 | RARG (0.54) | CYP26A1CYP26B1RXRARXRBRXRG | |
| SCHEMBL8189489 | 0.78 | RARG (0.54) | CYP26A1CYP26B1RXRARXRBRXRG | |
| SCHEMBL7872180 | 0.75 | CYP26A1 (0.59) | CYP26A1CYP26B1RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326510-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-12-04 | — | — | US | disclosed |