Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 3/20 | 0.51 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 6/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7872275 | 1.00 | CYP26A1 (0.51) | CYP26A1CYP26B1GLAMAPTSIRT2 | |
| SCHEMBL7872150 | 0.89 | GLA (0.59) | CYP26A1CYP26B1GLAMAPTMEN1 | |
| SCHEMBL7872151 | 0.89 | GLA (0.59) | CYP26A1CYP26B1GLAMAPTMEN1 | |
| SCHEMBL7872209 | 0.86 | RARA (0.55) | CYP26A1CYP26B1SIRT2SIRT1MEN1 | |
| SCHEMBL7872206 | 0.86 | RARA (0.55) | CYP26A1CYP26B1SIRT2SIRT1MEN1 | |
| SCHEMBL7900823 | 0.83 | RXRA (0.53) | CYP26A1CYP26B1MEN1KMT2ARXRA | |
| SCHEMBL7900821 | 0.83 | RXRA (0.53) | CYP26A1CYP26B1MEN1KMT2ARXRA | |
| SCHEMBL7876464 | 0.80 | CYP26A1 (0.47) | CYP26A1CYP26B1MEN1KMT2ASNCA | |
| SCHEMBL7876465 | 0.80 | CYP26A1 (0.47) | CYP26A1CYP26B1MEN1KMT2ASNCA | |
| SCHEMBL8445083 | 0.78 | CYP26A1 (0.73) | CYP26A1CYP26B1MEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326510-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-12-04 | — | — | US | disclosed |