Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12258804 | 0.86 | ALDH1A1 (0.51) | ALDH1A1CYP2D6KDM4EKMT2AEPHX1 | |
| SCHEMBL8193648 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CYP2D6KDM4EKMT2A | |
| SCHEMBL12870586 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CYP2D6KDM4EKMT2A | |
| SCHEMBL12869546 | 0.82 | ALDH1A1 (0.49) | ALDH1A1CYP2D6KDM4EKMT2A | |
| SCHEMBL7870008 | 0.78 | KDM4E (0.59) | KDM4EKMT2A | |
| SCHEMBL5240027 | 0.77 | KDM4E (0.63) | ALDH1A1CYP2D6KDM4EKMT2A | |
| SCHEMBL8437435 | 0.76 | ALDH1A1 (0.55) | ALDH1A1CYP2D6KDM4EKMT2A | |
| SCHEMBL4833027 | 0.72 | KDM4E (0.42) | ALDH1A1CYP2D6KDM4EKMT2A | |
| SCHEMBL21916515 | 0.72 | ALDH1A1 (0.41) | ALDH1A1CYP2D6KDM4EKMT2A | |
| SCHEMBL15461451 | 0.72 | ALDH1A1 (0.41) | ALDH1A1CYP2D6KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808303-B1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ASTRAZENECA AB (SE) | 2001-06-20 | — | — | EP | disclosed |
| EP-0808303-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024582-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1996-08-15 | — | — | WO | disclosed |