SCHEMBL7870008

SCHEMBL7870008

CNC1(C(N)=O)CC[N]CC1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.59
KMT2A Q03164 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3715654 0.84
SCHEMBL13448658 0.79 KDM4E (0.65) KDM4EKMT2A
SCHEMBL14533055 0.79
SCHEMBL8913688 0.78 CNR1 (0.38) KDM4EKMT2A
SCHEMBL7876466 0.78 ALDH1A1 (0.46) KDM4EKMT2A
SCHEMBL18122821 0.77 KDM4E (0.63) KDM4EKMT2A
SCHEMBL807124 0.74 KDM4E (1.00) KDM4EKMT2A
SCHEMBL18122804 0.74 KDM4E (0.59) KDM4EKMT2A
SCHEMBL13817485 0.72 KDM4E (0.57) KDM4EKMT2A
SCHEMBL10280093 0.72 KDM4E (0.57) KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0808303-B1 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST ASTRAZENECA AB (SE) 2001-06-20 EP disclosed
EP-0808303-A1 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST ZENECA LIMITED (GB) 1997-11-26 EP disclosed
WO-1996024582-A1 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST ZENECA LIMITED (GB) 1996-08-15 WO disclosed