Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7874455 | 0.92 | PTGS2 (0.67) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL7876594 | 0.88 | PTGS2 (0.70) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL7876348 | 0.87 | PTGS2 (0.65) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL8209186 | 0.86 | PTGS2 (0.56) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL7874468 | 0.86 | PTGS2 (0.70) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL7876235 | 0.86 | PTGS2 (0.73) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL6464094 | 0.85 | PTGS2 (0.84) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL8069691 | 0.85 | PTGS2 (0.65) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL8201312 | 0.85 | PTGS2 (0.53) | PTGS2PTGS1CYP2C9 | |
| Hydrochloric Acid SCHEMBL7874470 | 0.84 | PTGS2 (0.64) | PTGS2PTGS1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316485-B1 | INHIBITS ACTIVITY OF CYCLOOXYGENASE-2; FOR THERAPY AND PROPHYLAXIS OF INFLAMMATION, THROMBOSIS, RHEUMATOID ARTHRITIS, ALZHEIMER'S DISEASE; AS ANALGESIC | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |
| EP-1017678-A1 | 1,5-DIPHENYLPYRAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015505-A1 | 1,5-DIPHENYLPYRAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |