Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 10/20 | 0.64 |
| ▸ | RXRB | P28702 | 8/20 | 0.64 |
| ▸ | RXRG | P48443 | 6/20 | 0.64 |
| ▸ | CYP26A1 | O43174 | 7/20 | 0.56 |
| ▸ | CYP26B1 | Q9NR63 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | RARB | P10826 | 7/20 | 0.56 |
| ▸ | RARG | P13631 | 7/20 | 0.56 |
| ▸ | RARA | P10276 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8839076 | 0.88 | RXRA (0.71) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL9208986 | 0.84 | RXRA (0.78) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL8839146 | 0.82 | RXRA (0.67) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL6147923 | 0.82 | RXRA (0.67) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL8676840 | 0.80 | RXRB (0.71) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL5083941 | 0.79 | RXRA (0.66) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL21776768 | 0.79 | CYP26B1 (0.83) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL29605538 | 0.79 | CYP26B1 (0.83) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL9165893 | 0.78 | RXRA (0.69) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL8674842 | 0.77 | RXRA (0.68) | RXRARXRBRXRGCYP26A1CYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326510-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-12-04 | — | — | US | claimed |
| US-6326510-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-12-04 | — | — | US | disclosed |