Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.53 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL618203 | 0.82 | GABBR2 (0.55) | GABBR2GABBR1CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL618204 | 0.82 | GABBR2 (0.55) | GABBR2GABBR1CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL10022854 | 0.82 | GABBR2 (0.55) | GABBR2GABBR1CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL1667437 | 0.78 | GABBR2 (0.52) | GABBR2GABBR1CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL1666942 | 0.78 | GABBR2 (0.52) | GABBR2GABBR1LMNAADRA2AADRA2C | |
| SCHEMBL1669595 | 0.78 | GABBR2 (0.52) | GABBR2GABBR1LMNACYP2C19KMT2A | |
| SCHEMBL1667061 | 0.78 | GABBR2 (0.52) | GABBR2GABBR1CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL5144343 | 0.78 | GABBR2 (0.52) | GABBR2GABBR1ADRA2AADRA2CCYP2C19 | |
| SCHEMBL30864435 | 0.78 | GRM4 (0.48) | LMNAKMT2A | |
| SCHEMBL30864434 | 0.78 | GRM4 (0.48) | LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313094-B1 | COMPOSITION FOR INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | JAPAN ENERGY CORPORATION (JP) | 2001-11-06 | — | — | US | disclosed |