Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.55 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 2/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | CPA3 | P15088 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10022854 | 1.00 | GABBR2 (0.55) | GABBR2GABBR1CYP2C19TACR1KMT2A | |
| SCHEMBL618204 | 1.00 | GABBR2 (0.55) | GABBR2GABBR1CYP2C19TACR1KMT2A | |
| SCHEMBL19143349 | 0.84 | TACR1 (0.43) | GABBR2GABBR1CYP2C19TACR1SMN1; SMN2 | |
| SCHEMBL31369450 | 0.82 | CYP2C9 (0.60) | GABBR2GABBR1CYP2C19KMT2ACYP2D6 | |
| SCHEMBL7876564 | 0.82 | GABBR2 (0.53) | GABBR2GABBR1CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL1667061 | 0.80 | GABBR2 (0.52) | GABBR2GABBR1CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL1667437 | 0.80 | GABBR2 (0.52) | GABBR2GABBR1CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL5144343 | 0.80 | GABBR2 (0.52) | GABBR2GABBR1CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL1666942 | 0.80 | GABBR2 (0.52) | GABBR2GABBR1CYP2C19MAPT | |
| SCHEMBL1669595 | 0.80 | GABBR2 (0.52) | GABBR2GABBR1CYP2C19KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3208279-B1 | MINI-HEPCIDIN PEPTIDES AND METHODS OF USING THEREOF | UNIV CALIFORNIA (US) | 2021-04-21 | — | — | EP | claimed |
| US-9896481-B2 | Modified mini-hepcidin peptides and methods of using thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-02-20 | — | — | US | claimed |
| EP-2373679-B1 | MINI-HEPCIDIN PEPTIDES AND METHODS OF USING THEREOF | UNIV CALIFORNIA (US) | 2017-03-08 | — | — | EP | claimed |
| US-8435941-B2 | Mini-hepcidin peptides and methods of using thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-05-07 | — | — | US | claimed |
| US-11702652-B2 | Enzymatic encoding methods for efficient synthesis of large libraries | NUEVOLUTION A/S (DK) | 2023-07-18 | — | — | US | disclosed |
| US-11702652-B2 | Enzymatic encoding methods for efficient synthesis of large libraries | NUEVOLUTION A/S (DK) | 2023-07-18 | — | — | US | disclosed |
| EP-3305900-B1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | NUEVOLUTION AS (DK) | 2021-07-21 | — | — | EP | disclosed |
| US-20210128690-A1 | METHODS OF ADMINISTERING HEPCIDIN | LA JOLLA PHARMACEUTICAL COMPANY | 2021-05-06 | — | — | US | disclosed |
| EP-3208279-B1 | MINI-HEPCIDIN PEPTIDES AND METHODS OF USING THEREOF | UNIV CALIFORNIA (US) | 2021-04-21 | — | — | EP | disclosed |
| EP-3240799-B1 | S-ALKYLATED HEPCIDIN PEPTIDES AND METHODS OF MAKING AND USING THEREOF | UNIV CALIFORNIA (US) | 2021-03-31 | — | — | EP | disclosed |
| US-10947274-B1 | Synthetic analgesic peptides of RgIA analogs | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2021-03-16 | — | — | US | disclosed |
| US-20200216836-A1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | NUEVOLUTION A/S (DK) | 2020-07-09 | — | — | US | disclosed |
| US-8435941-B2 | Mini-hepcidin peptides and methods of using thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-05-07 | — | — | US | disclosed |
| US-20120040894-A1 | Mini-Hepcidin Peptides and Methods of Using thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-02-16 | — | — | US | disclosed |
| EP-2341140-A1 | Enzymatic encoding methods for efficient synthesis of large libraries | Nuevolution A/S (DK) | 2011-07-06 | — | — | EP | disclosed |
| EP-2336315-A2 | Enzymatic encoding methods for efficient synthesis of large libraries | Nuevolution A/S (DK) | 2011-06-22 | — | — | EP | disclosed |
| EP-1957644-B1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | NUEVOLUTION AS (DK) | 2010-12-01 | — | — | EP | disclosed |
| US-20090264300-A1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | NUEVOLUTION A/S (DK) | 2009-10-22 | — | — | US | disclosed |
| US-20090264300-A1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | NUEVOLUTION A/S (DK) | 2009-10-22 | — | — | US | disclosed |
| WO-2007062664-A2 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | NUEVOLUTION A/S (DK) | 2007-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264300-A1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | RNGTT, DUT, EMG1 | GABBR2 3935/4885GABBR1 3901/4885CYP2C19 3026/4885 |
| US-20210128690-A1 | METHODS OF ADMINISTERING HEPCIDIN | HAMP, FTH1, HDGF | GABBR2 3526/4885GABBR1 3818/4885CYP2C19 4020/4885 |
| US-20120040894-A1 | Mini-Hepcidin Peptides and Methods of Using thereof | HAMP, VIP, SPPL2B | GABBR2 4347/4885GABBR1 4536/4885CYP2C19 3866/4885 |
| US-10947274-B1 | Synthetic analgesic peptides of RgIA analogs | QRFPR, OPRL1, VIP | GABBR2 1369/4885GABBR1 1876/4885CYP2C19 3655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.