SCHEMBL7876673

SCHEMBL7876673

O=[N+]([O-])c1[c]cc(Oc2ccc(C(F)(F)F)cc2Cl)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
TTR P02766 1/20 0.57
PPOX P50336 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
FFAR1 O14842 5/20 0.47
PDE7A Q13946 1/20 0.42
LMNA P02545 4/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
HPGD P15428 2/20 0.39
POLB P06746 2/20 0.38
MAPT P10636 2/20 0.38
HTR2A P28223 1/20 0.38
SLC6A4 P31645 1/20 0.38
KCNH2 Q12809 1/20 0.38
CCR6 P51684 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
GPR55 Q9Y2T6 1/20 0.38
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29052277 0.83 TDP1 (0.50) MEN1KMT2ATTRTDP1FFAR1
SCHEMBL7717699 0.83 MEN1 (0.57) MEN1KMT2ATTRPPOXTDP1
SCHEMBL11039735 0.81 TDP1 (0.38) MEN1KMT2ATTRPPOXTDP1
Nitrofluorfen SCHEMBL8537296 0.81 MEN1 (0.63) MEN1KMT2ATTRPPOXTDP1
Nitrofluorfen SCHEMBL29370618 0.81 MEN1 (0.63) MEN1KMT2ATTRPPOXTDP1
Nitrofluorfen SCHEMBL39312 0.81 MEN1 (0.63) MEN1KMT2ATTRPPOXTDP1
Nitrofluorfen SCHEMBL11297390 0.80 MEN1 (0.62) MEN1KMT2ATTRPPOXTDP1
Nitrofluorfen SCHEMBL11297383 0.80 MEN1 (0.62) MEN1KMT2ATTRPPOXTDP1
SCHEMBL10706908 0.79 TDP1 (0.74) MEN1KMT2ATTRPPOXTDP1
SCHEMBL8694365 0.79 TDP1 (0.74) MEN1KMT2ATTRPPOXTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2668156-B1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2018-10-31 EP claimed
US-20160060214-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2016-03-03 US claimed
EP-2668156-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2013-12-04 EP claimed
US-20130308219-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2013-11-21 US claimed
WO-2012101245-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2012-08-02 WO claimed
CN-111559965-B Substituted benzoyl compounds and application thereof in agriculture 东莞市东阳光农药研发有限公司 2022-11-18 CN disclosed
CN-111559965-A Substituted benzoyl compounds and application thereof in agriculture 东莞市东阳光农药研发有限公司 2020-08-21 CN disclosed
US-20190171099-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2019-06-06 US disclosed
US-10241399-B2 Polymerizable composition comprising an oxime sulfonate as thermal curing agent BASF SE (DE) 2019-03-26 US disclosed
EP-2668156-B1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2018-10-31 EP disclosed
US-9310677-B2 Polymerizable composition comprising an oxime sulfonate as thermal curing agent BASF (DE) 2016-04-12 US disclosed
US-20160060214-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2016-03-03 US disclosed
US-6013836-A PARTICULARLY ACTIVE AGAINST MOTHS AND BEETLES AND THEIR INSECT GROWTH REGULATING ACTIVITY WITHOUT ADVERSE IMPACT ON BENEFICIAL INSECTS; CROPS; FORESTRY ROHM AND HAAS COMPANY (US) 2000-01-11 US disclosed
US-4633000-A 2-nitro-5-(substituted-phenoxy) phenylalkanone oxime and imine derivatives as herbicides RHONE POULENC AGROCHIMIE (FR) 1986-12-30 US disclosed
US-4551171-A 2-Nitro-5-(substituted-phenoxy) phenylalkanone oxime and imine derivatives as herbicides RHONE-POULENC, INC. (US) 1985-11-05 US disclosed
US-4517010-A 2-Nitro-5(substituted-phenoxy) benzoyl derivatives as herbicides RHONE-POULENC INC. (US) 1985-05-14 US disclosed
EP-0034012-B1 2-NITRO-5-(SUBSTITUTED-PHENOXY) PHENYLALKANONE OXIME AND IMINE DERIVATIVES AS HERBICIDES RHONE-POULENC AGROCHIMIE (FR) 1984-09-12 EP disclosed
EP-0043801-A2 2-Substituted 5-phenoxy-phenyl-phosphinic-acid derivatives with herbicidal activity, process for preparing them, herbicidal compositions containing them and use of these active substances and compositions CIBA-GEIGY AG (CH) 1982-01-13 EP disclosed
EP-0034883-A1 2-Nitro-5-(substituted-phenoxy) benzoyl derivatives as herbicides RHONE-POULENC INC. (US) 1981-09-02 EP disclosed
EP-0034012-A2 2-nitro-5-(substituted-phenoxy) phenylalkanone oxime and imine derivatives as herbicides RHONE-POULENC AGROCHIMIE (FR) 1981-08-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10241399-B2 Polymerizable composition comprising an oxime sulfonate as thermal curing agent SULT1E1, COX6B1, SULT1A1 MEN1 4751/4885KMT2A 930/4885TTR 4279/4885
US-20190171099-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT SULT1E1, COX6B1, SULT1A1 MEN1 4751/4885KMT2A 930/4885TTR 4279/4885
US-20160060214-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT SULT1E1, COX6B1, SULT1A1 MEN1 4751/4885KMT2A 930/4885TTR 4279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.