SCHEMBL787679

SCHEMBL787679

c1ccc(-c2ccnc(-c3ccccn3)c2-c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 2/20 0.46
KDM4E B2RXH2 5/20 0.45
LMNA P02545 4/20 0.45
CCR1 P32246 2/20 0.45
CCR5 P51681 2/20 0.45
CCR8 P51685 2/20 0.45
CYP1A2 P05177 1/20 0.45
POLB P06746 1/20 0.45
METAP1 P53582 1/20 0.45
BLM P54132 1/20 0.45
HIF1A Q16665 1/20 0.45
DOHH Q9BU89 1/20 0.45
P4HTM Q9NXG6 1/20 0.45
NPY5R Q15761 1/20 0.44
CYP2A6 P11509 1/20 0.42
KDR P35968 1/20 0.41
MCL1 Q07820 2/20 0.40
NPC1 O15118 4/20 0.40
TP53 P04637 4/20 0.40
RAB9A P51151 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyridyl SCHEMBL4595525 0.98 KDM4E (0.48) TGFBR1KDM4ELMNACCR1CCR5
Hydrochloric Acid SCHEMBL1572132 0.98 TGFBR1 (0.45) TGFBR1KDM4ELMNACCR1CCR5
Hydrochloric Acid SCHEMBL2455950 0.98 TGFBR1 (0.45) TGFBR1KDM4ELMNACCR1CCR5
SCHEMBL32689469 0.98 TGFBR1 (0.45) TGFBR1KDM4ELMNACCR1CCR5
Dipyridyl SCHEMBL7511159 0.98 KDM4E (0.48) TGFBR1KDM4ELMNACCR1CCR5
SCHEMBL29942138 0.95 TGFBR1 (0.47) TGFBR1KDM4ELMNACCR1CCR5
SCHEMBL923478 0.95 TGFBR1 (0.47) TGFBR1KDM4ELMNACCR1CCR5
SCHEMBL2455952 0.94 TGFBR1 (0.42) TGFBR1KDM4ELMNACCR1CCR5
SCHEMBL6381236 0.90 TGFBR1 (0.42) TGFBR1KDM4ELMNACCR1CCR5
SCHEMBL3169261 0.87 TGFBR1 (0.51) TGFBR1KDM4ELMNACCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114953672-B Wallboard and preparation process thereof 常州市贝美家居科技有限公司 2023-06-09 CN claimed
US-5439794-A Spectroscopically or photoactively determination when bound to Dna THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1995-08-08 US claimed
US-5432101-A Complex consists of biologically active molecule associated by coupling or adsorption with the complex COMPAGNIE ORIS INDUSTRIE SA (FR) 1995-07-11 US claimed
US-5220012-A Macropolycyclic rare earth complexes and application as fluorescent tracers COMPAGNIE ORIS INDUSTRIE SA (FR) 1993-06-15 US claimed
US-5112974-A Targets tumor cells for radiation treatment, metal complexes with amines or imines THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1992-05-12 US claimed
WO-1990005732-A1 MIXED LIGAND COMPLEXES AND USES THEREOF AS BINDING AGENTS AND PROBRES TO DNA THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OFNEW YORK (US) 1990-05-31 WO claimed
EP-0180492-A1 Macropolycyclic complexes of rare earth metals and application as fluorescent labels CIS BIO INTERNATIONAL (FR) 1986-05-07 EP claimed
EP-4486924-A2 NUCLEIC ACID CROSSLINKING REAGENTS AND USES THEREOF Promega Corporation (US) 2025-01-08 EP disclosed
CN-119191978-A Method for synthesizing meta-secondary alkyl substituted aryl carboxylic acid 华南理工大学 2024-12-27 CN disclosed
CN-117913198-A Panel substrate, method for manufacturing micro LED display device and display device 乐金显示有限公司 2024-04-19 CN disclosed
CN-117586106-A Method for synthesizing alkylaryl ether 中国人民解放军空军军医大学 2024-02-23 CN disclosed
WO-2023177976-A2 NUCLEIC ACID CROSSLINKING REAGENTS AND USES THEREOF PROMEGA CORPORATION (US) 2023-09-21 WO disclosed
EP-4208564-A1 NUCLEIC ACID MODIFYING REAGENTS AND USES THEREOF Promega Corporation (US) 2023-07-12 EP disclosed
WO-1994014620-A1 THERMOGRAPHIC IMAGE-RECORDING MATERIAL POLAROID CORPORATION (US) 1994-07-07 WO disclosed
US-5220012-A Macropolycyclic rare earth complexes and application as fluorescent tracers COMPAGNIE ORIS INDUSTRIE SA (FR) 1993-06-15 US disclosed
EP-0180492-B1 MACROPOLYCYCLIC COMPLEXES OF RARE EARTH METALS AND APPLICATION AS FLUORESCENT LABELS CIS BIO INTERNATIONAL (FR) 1993-06-02 EP disclosed
US-5112974-A Targets tumor cells for radiation treatment, metal complexes with amines or imines THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1992-05-12 US disclosed
WO-1990005732-A1 MIXED LIGAND COMPLEXES AND USES THEREOF AS BINDING AGENTS AND PROBRES TO DNA THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OFNEW YORK (US) 1990-05-31 WO disclosed
US-4927923-A IMMUNOLOGY COMPAGNIE ORIS INDUSTRIES (FR) 1990-05-22 US disclosed
EP-0180492-A1 Macropolycyclic complexes of rare earth metals and application as fluorescent labels CIS BIO INTERNATIONAL (FR) 1986-05-07 EP disclosed