SCHEMBL3169261

SCHEMBL3169261

Fc1ccc(-c2ccnc(-c3ccccn3)c2-c2ccc(F)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 5/20 0.51
MAPK14 Q16539 1/20 0.51
THRB P10828 1/20 0.50
MCL1 Q07820 1/20 0.45
SQOR Q9Y6N5 3/20 0.43
DCTPP1 Q9H773 1/20 0.42
TOP1 P11387 2/20 0.40
CDK1 P06493 1/20 0.40
CDK4 P11802 1/20 0.40
CCNB1 P14635 1/20 0.40
CCNA2 P20248 1/20 0.40
CCND1 P24385 1/20 0.40
CDK2 P24941 1/20 0.40
CDK7 P50613 1/20 0.40
CCNH P51946 1/20 0.40
LMNA P02545 2/20 0.39
KDM4E B2RXH2 1/20 0.39
CYP1A2 P05177 1/20 0.39
POLB P06746 1/20 0.39
CCR1 P32246 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL787679 0.87 TGFBR1 (0.46) TGFBR1MCL1CDK7LMNAKDM4E
Dipyridyl SCHEMBL7511159 0.85 KDM4E (0.48) TGFBR1MCL1CDK7LMNAKDM4E
Hydrochloric Acid SCHEMBL2455950 0.85 TGFBR1 (0.45) TGFBR1MCL1CDK7LMNAKDM4E
SCHEMBL32689469 0.85 TGFBR1 (0.45) TGFBR1MCL1CDK7LMNAKDM4E
Dipyridyl SCHEMBL4595525 0.85 KDM4E (0.48) TGFBR1MCL1CDK7LMNAKDM4E
Hydrochloric Acid SCHEMBL1572132 0.85 TGFBR1 (0.45) TGFBR1MCL1CDK7LMNAKDM4E
SCHEMBL31058350 0.84 ULK1 (0.42) TGFBR1THRBCDK7LMNAKDM4E
SCHEMBL29942138 0.82 TGFBR1 (0.47) TGFBR1MCL1CDK7LMNAKDM4E
SCHEMBL923478 0.82 TGFBR1 (0.47) TGFBR1MCL1CDK7LMNAKDM4E
SCHEMBL2455952 0.81 TGFBR1 (0.42) TGFBR1MAPK14MCL1CDK7LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1554361-B1 METALLIC COMPLEXES COVALENTLY BOUND TO CONJUGATED POLYMERS AND ELECTRONIC DEVICES CONTAINING SUCH COMPOSITIONS DU PONT (US) 2010-03-17 EP disclosed
US-7575816-B2 Luminescent lanthanide complexes with imine ligands and devices made with such complexes E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-08-18 US disclosed
US-7090929-B2 Metallic complexes covalently bound to conjugated polymers and electronic devices containing such compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 2006-08-15 US disclosed
US-20050233233-A1 Luminescent lanthanide complexes with imine ligands and devices made with such complexes RADU NORA S 2005-10-20 US disclosed
US-20050233232-A1 Luminescent lanthanide complexes with imine ligands and devices made with such complexes LG CHEM, LTD. (KR) 2005-10-20 US disclosed
US-6924047-B2 Luminescent lanthanide complexes with imine ligands and devices made with such complexes E.I. DU PONT DE NEMOURS AND COMPANY (US) 2005-08-02 US disclosed
EP-1554361-A1 METALLIC COMPLEXES COVALENTLY BOUND TO CONJUGATED POLYMERS AND ELECTRONIC DEVICES CONTAINING SUCH COMPOSITIONS E. I. du Pont de Nemours and Company (US) 2005-07-20 EP disclosed
US-20040072018-A1 Metallic complexes covalently bound to conjugated polymers and electronic devices containing such compositions LG CHEM, LTD. (KR) 2004-04-15 US disclosed
WO-2004015025-A1 METALLIC COMPLEXES COVALENTLY BOUND TO CONJUGATED POLYMERS AND ELECTRONIC DEVICES CONTAINING SUCH COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2004-02-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050233233-A1 Luminescent lanthanide complexes with imine ligands and devices made with such complexes SSB, LARP7, LIG3 TGFBR1 4074/4885MAPK14 4190/4885THRB 4245/4885
US-20050233232-A1 Luminescent lanthanide complexes with imine ligands and devices made with such complexes SSB, LARP7, LIG3 TGFBR1 4074/4885MAPK14 4190/4885THRB 4245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.