Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867807 | 0.78 | SLC6A2 (0.49) | HTR1ASLC6A2SLC6A4SLC6A3CHRNB2 | |
| Hydrochloric Acid SCHEMBL7874318 | 0.77 | SLC6A2 (0.48) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5115814 | 0.76 | ADRA1D (0.43) | SCN9AADRA1DADRA1AADRA1BADRA2A | |
| SCHEMBL3749991 | 0.73 | SCN9A (0.44) | SCN9AFFAR4SLC22A12EPAS1HCRTR1 | |
| SCHEMBL24877474 | 0.72 | SLC6A2 (0.38) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| SCHEMBL8003983 | 0.71 | ADRA1D (0.47) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| SCHEMBL7661363 | 0.69 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| SCHEMBL7965565 | 0.69 | TRPC3 (0.38) | FFAR4HTR1A | |
| SCHEMBL7876830 | 0.69 | OPRL1 (0.42) | FFAR4ADRA1DADRA1AADRA1BADRA2A | |
| SCHEMBL24877518 | 0.69 | DRD2 (0.41) | ADRA1DADRA1AADRA1BADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316437-B1 | ADRENERGIC RECEPTOR ANTAGONISTS | MERCK & CO., INC. | 2001-11-13 | — | — | US | disclosed |