⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18649391 | 0.82 | KIF11 (0.32) | — | |
| SCHEMBL7878737 | 0.78 | CYP11B2 (0.41) | — | |
| SCHEMBL16230231 | 0.77 | CYP3A4 (0.38) | — | |
| SCHEMBL19310947 | 0.76 | HCAR2 (0.38) | — | |
| SCHEMBL13278943 | 0.76 | KDM4E (0.38) | — | |
| SCHEMBL18698031 | 0.72 | CYP11B2 (0.44) | — | |
| SCHEMBL18697961 | 0.70 | — | — | |
| SCHEMBL8863475 | 0.69 | CYP19A1 (0.45) | — | |
| SCHEMBL18698010 | 0.69 | CYP11B2 (0.41) | — | |
| SCHEMBL18698005 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139747-A1 | 1H-IMIDAZO[4, 5-c]QUINOLINONE COMPOUNDS, USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2010-12-09 | — | — | WO | disclosed |