Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805565 | 1.00 | ALDH1A1 (0.56) | ALDH1A1CYP1A2NPSR1TSHRHTT | |
| SCHEMBL8804897 | 0.95 | ALDH1A1 (0.51) | ALDH1A1CYP1A2NPSR1TSHRHTT | |
| SCHEMBL3414946 | 0.87 | ALDH1A1 (0.70) | ALDH1A1CYP1A2NPSR1TSHRHTT | |
| SCHEMBL16811748 | 0.85 | ALDH1A1 (0.56) | ALDH1A1CYP1A2NPSR1TSHRHTT | |
| SCHEMBL8330910 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP1A2NPSR1TSHRHTT | |
| SCHEMBL27166962 | 0.83 | ALDH1A1 (0.48) | ALDH1A1CYP1A2NPSR1TSHRHTT | |
| SCHEMBL2353735 | 0.83 | ALDH1A1 (0.74) | ALDH1A1CYP1A2NPSR1TSHRTDP1 | |
| SCHEMBL4797060 | 0.83 | ALDH1A1 (0.54) | ALDH1A1CYP1A2NPSR1TSHRHTT | |
| SCHEMBL7874932 | 0.81 | ALDH1A1 (0.51) | ALDH1A1CYP1A2NPSR1TSHRHTT | |
| SCHEMBL8808456 | 0.81 | ALDH1A1 (0.57) | ALDH1A1CYP1A2NPSR1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310083-B1 | DERIVATIVES OF O-NITROMANDELYOXYCARBONYL WHICH ARE CAPABLE OF RELEASING AMINO ACIDS (OR DERIVATIVES THEREOF) UPON IRRADIATION WITH ULTRAVIOLET LIGHT; PRODUCING AMINO ACIDS (OR DERIVATIVES THEREOF) FOR USE IN NEUROPHYSIOLOGY STUDIES | UNIVERSITY OF MARYLAND BOITECHNOLOGY INSTITUTE | 2001-10-30 | — | — | US | disclosed |
| US-5635608-A | CONTAINS PHOTOREMOVABLE ALPHA-CARBOXY-SUBSTITUTED ORTHO-NITROBENZYL GROUP THAT CHANGES THE FLUORESCENCE AND BIOLOGICAL PROPERTIES OF THE COMPOUND | MOLECULAR PROBES, INC. (US) | 1997-06-03 | — | — | US | disclosed |