SCHEMBL7874932

SCHEMBL7874932

CC(=O)OC(C(=O)OC(C)(C)C)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.51
CYP1A2 P05177 2/20 0.43
NPSR1 Q6W5P4 2/20 0.41
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.40
MAPT P10636 4/20 0.37
POLB P06746 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
THRB P10828 1/20 0.36
CDK5 Q00535 1/20 0.36
CDK5R1 Q15078 1/20 0.36
ITGA4 P13612 1/20 0.36
ITGB7 P26010 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP3A4 P08684 1/20 0.35
PDK1 Q15118 1/20 0.35
PDK2 Q15119 1/20 0.35
PDK3 Q15120 1/20 0.35
PDK4 Q16654 1/20 0.35
GAA P10253 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8804890 0.88 ALDH1A1 (0.50) ALDH1A1CYP1A2NPSR1TSHRHTT
SCHEMBL8804894 0.88 ALDH1A1 (0.50) ALDH1A1CYP1A2NPSR1TSHRHTT
SCHEMBL27166846 0.85 ALDH1A1 (0.44) ALDH1A1CYP1A2NPSR1TSHRHTT
SCHEMBL7877336 0.82 CYP1A2 (0.55) ALDH1A1CYP1A2NPSR1TSHRHTT
SCHEMBL3414946 0.82 ALDH1A1 (0.70) ALDH1A1CYP1A2NPSR1TSHRHTT
SCHEMBL16811748 0.81 ALDH1A1 (0.56) ALDH1A1CYP1A2NPSR1TSHRHTT
SCHEMBL8805565 0.81 ALDH1A1 (0.56) ALDH1A1CYP1A2NPSR1TSHRHTT
SCHEMBL7877446 0.81 ALDH1A1 (0.56) ALDH1A1CYP1A2NPSR1TSHRHTT
SCHEMBL8330910 0.80 ALDH1A1 (0.55) ALDH1A1CYP1A2NPSR1TSHRHTT
SCHEMBL17094771 0.77 ALDH1A1 (0.42) ALDH1A1CYP1A2NPSR1TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6310083-B1 DERIVATIVES OF O-NITROMANDELYOXYCARBONYL WHICH ARE CAPABLE OF RELEASING AMINO ACIDS (OR DERIVATIVES THEREOF) UPON IRRADIATION WITH ULTRAVIOLET LIGHT; PRODUCING AMINO ACIDS (OR DERIVATIVES THEREOF) FOR USE IN NEUROPHYSIOLOGY STUDIES UNIVERSITY OF MARYLAND BOITECHNOLOGY INSTITUTE 2001-10-30 US disclosed