Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAT1 | P21673 | 1/20 | 0.73 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.55 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.55 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.55 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528896 | 0.89 | SAT1 (0.76) | SAT1GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL17355046 | 0.89 | SAT1 (0.61) | SAT1GNAI3GNAO1GNAI1PAOX | |
| SCHEMBL7201037 | 0.89 | SAT1 (0.74) | SAT1GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL7202965 | 0.89 | SAT1 (0.74) | SAT1GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL7207742 | 0.89 | SAT1 (0.74) | SAT1GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL11420212 | 0.89 | SAT1 (0.60) | SAT1GNAI3GNAO1GNAI1PAOX | |
| SCHEMBL95570 | 0.89 | — | — | |
| SCHEMBL23468518 | 0.87 | GNAI3 (0.70) | SAT1GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL10045082 | 0.87 | SAT1 (0.96) | SAT1GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL23468533 | 0.87 | GNAI3 (0.70) | SAT1GNAI3GNAO1GNAI1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6319956-B1 | N1, N4-BIS(CYCLOPROPYLMETHYLAMINO)TRIALKYLENETETRAMINES THAT MAY BE TOLUENESULFONATED. | RIKEN (JP) | 2001-11-20 | — | — | US | disclosed |