SCHEMBL787779

SCHEMBL787779

CC1=C(C#N)C(=C(C#N)C#N)OC1(c1cccc(-c2ccccc2)c1)C(F)(F)F

nearest known ligand 0.80

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 9/20 0.80
MEN1 O00255 1/20 0.32
PRNP P04156 1/20 0.32
PPARG P37231 1/20 0.32
KMT2A Q03164 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
RCE1 Q9Y256 1/20 0.32
NR2E3 Q9Y5X4 1/20 0.32
NCOR2 Q9Y618 1/20 0.32
PDK2 Q15119 2/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
MGAT2 Q10469 3/20 0.31
PTPN5 P54829 1/20 0.31
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL406234 0.90 GPR35 (1.00) GPR35MEN1PRNPPPARGKMT2A
SCHEMBL25594138 0.90 GPR35 (1.00) GPR35MEN1PRNPPPARGKMT2A
SCHEMBL12837301 0.79 GPR35 (0.79) GPR35
SCHEMBL13302913 0.79 GPR35 (0.79) GPR35
SCHEMBL22830503 0.78 GPR35 (0.79) GPR35AR
SCHEMBL16158292 0.78 GPR35 (0.67) GPR35MEN1PRNPPPARGKMT2A
SCHEMBL14067285 0.77 GPR35 (0.76) GPR35
SCHEMBL24141613 0.76 GPR35 (0.63) GPR35MEN1PRNPPPARGKMT2A
SCHEMBL24960473 0.75 GPR35 (0.73) GPR35MEN1PRNPPPARGKMT2A
SCHEMBL22862899 0.74 GPR35 (0.72) GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9703128-B2 Method for making an integrated circuit having optical data communication BrPhotonics Produtos Optoeletronicos LTDA (BR) 2017-07-11 US disclosed
US-20160349547-A1 METHOD FOR MAKING AN INTEGRATED CIRCUIT HAVING OPTICAL DATA COMMUNICATION LIGHTWAVE LOGIC, INC. 2016-12-01 US disclosed
US-8934741-B2 Integrated circuit with optical data communication Brphotonics Produtos Optoelectronicos LTDA (BR) 2015-01-13 US disclosed
US-20140302250-A1 ELECTRO-OPTIC POLYMER AND ELECTRO-OPTIC DEVICES MADE THEREFROM GIGOPTIX, INC. (US) 2014-10-09 US disclosed
US-8618241-B2 Stabilized electro-optic materials and electro-optic devices made therefrom GIGOPTIX, INC. (US) 2013-12-31 US disclosed
US-20120163749-A1 INTEGRATED CIRCUIT WITH OPTICAL DATA COMMUNICATION GIGOPTIX, INC. (US) 2012-06-28 US disclosed
US-20120157584-A1 STABILIZED ELECTRO-OPTIC MATERIALS AND ELECTRO-OPTIC DEVICES MADE THEREFROM GIGOPTIX, INC. (US) 2012-06-21 US disclosed
WO-2012037377-A2 INTEGRATED CIRCUIT WITH OPTICAL DATA COMMUNICATION GIGOPTIX, INC. (US) 2012-03-22 WO disclosed
WO-2012037372-A2 STABILIZED ELECTRO-OPTIC MATERIALS AND ELECTRO-OPTIC DEVICES MADE THEREFROM GIGOPTIX, INC. (US) 2012-03-22 WO disclosed