SCHEMBL406234

SCHEMBL406234

CC1=C(C#N)C(=C(C#N)C#N)OC1(c1ccccc1)C(F)(F)F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 9/20 1.00
MEN1 O00255 1/20 0.32
PRNP P04156 1/20 0.32
PPARG P37231 1/20 0.32
KMT2A Q03164 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
RCE1 Q9Y256 1/20 0.32
NR2E3 Q9Y5X4 1/20 0.32
NCOR2 Q9Y618 1/20 0.32
MGAT2 Q10469 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25594138 1.00 GPR35 (1.00) GPR35MEN1PRNPPPARGKMT2A
SCHEMBL787778 0.93 GPR35 (0.86) GPR35MEN1PRNPPPARGKMT2A
SCHEMBL787779 0.90 GPR35 (0.80) GPR35MEN1PRNPPPARGKMT2A
SCHEMBL12837301 0.88 GPR35 (0.79) GPR35
SCHEMBL13302913 0.88 GPR35 (0.79) GPR35
SCHEMBL22830503 0.88 GPR35 (0.79) GPR35
SCHEMBL14067285 0.86 GPR35 (0.76) GPR35
SCHEMBL24960473 0.84 GPR35 (0.73) GPR35MEN1PRNPPPARGKMT2A
SCHEMBL22862899 0.84 GPR35 (0.72) GPR35
SCHEMBL20954432 0.82 GPR35 (0.69) GPR35MGAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026100379-A1 COMPOSITION, NONLINEAR OPTICAL FILM, METHOD FOR FORMING NONLINEAR OPTICAL FILM, AND OPTICAL MODULATOR 三菱ケミカル株式会社 2026-05-15 WO disclosed
WO-2026089936-A1 NONLINEAR OPTICAL CHROMOPHORES CONTAINING 3-METHYL-2-CYCLOPENTEN-1-ONE BASED BRIDGE STRUCTURES, AND METHODS OF MAKING AND USING THE SAME LIGHTWAVE LOGIC, INC. (US) 2026-04-30 WO disclosed
US-20260098206-A1 Nonlinear Optical Chromophores Containing Donors with Substituents Giving High Steric Hinderance, and Methods of Making and Using the Same LIGHTWAVE LOGIC, INC. (US) 2026-04-09 US disclosed
US-20260093155-A1 Nonlinear Optical Chromophores with New Donors that Increase Refractive Index LIGHTWAVE LOGIC, INC. (US) 2026-04-02 US disclosed
US-20260085236-A1 Chromophores with New Bridges that Increase Refractive Index LIGHTWAVE LOGIC, INC. (US) 2026-03-26 US disclosed
US-20260085189-A1 Chromophores with New Ring-Locked Donors that Increase r33 and Stability LIGHTWAVE LOGIC, INC. (US) 2026-03-26 US disclosed
WO-2025261907-A1 NONLINEAR OPTICAL DYES WITH IMPROVED STABILITY SILORIX GMBH (DE) 2025-12-26 WO disclosed
EP-4667535-A1 NONLINEAR OPTICAL DYES WITH IMPROVED STABILITY SilOriX GmbH (DE) 2025-12-24 EP disclosed
US-20250206974-A1 ELECTRO-OPTIC INK COMPOSITION, COMPOUND, ELECTRO-OPTIC FILM, AND ELECTRO-OPTIC ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-06-26 US disclosed
US-20250154340-A1 COMPOSITION CONTAINING NONLINEAR OPTICALLY ACTIVE COPOLYMER NISSAN CHEMICAL CORPORATION (JP) 2025-05-15 US disclosed
WO-2011081970-A2 MOLECULES RELATED hERG Ion CHANNELS AND THE USE THEREOF CORNING INCORPORATED (US) 2011-07-07 WO disclosed
WO-2011081970-A2 MOLECULES RELATED hERG Ion CHANNELS AND THE USE THEREOF CORNING INCORPORATED (US) 2011-07-07 WO disclosed
WO-2011024774-A1 SECOND-ORDER NON-LINEAR OPTICAL COMPOUND AND NON-LINEAR OPTICAL ELEMENT COMPRISING SAME 独立行政法人情報通信研究機構 (JP) 2011-03-03 WO disclosed
US-7749408-B2 Electro-optic dendrimer-based glass composites UNIVERSITY OF WASHINGTON (US) 2010-07-06 US disclosed
US-20100152338-A1 NONLINEAR OPTICAL MATERIAL COMPOSITION AND METHOD OF MANUFACTURE NITTO DENKO CORPORATION (JP) 2010-06-17 US disclosed
US-20100152338-A1 NONLINEAR OPTICAL MATERIAL COMPOSITION AND METHOD OF MANUFACTURE NITTO DENKO CORPORATION (JP) 2010-06-17 US disclosed
US-20100029953-A1 PHENYLTETRAENE-BASED NONLINEAR OPTICAL CHROMOPHORES WASHINGTON, UNIVERSITY OF (US) 2010-02-04 US disclosed
US-20090118521-A1 NANOENGINEERED ORGANIC NONLINEAR OPTICAL GLASSES WASHINGTON, UNIVERSITY OF (US) 2009-05-07 US disclosed
US-20070152198-A1 ELECTRO-OPTIC DENDRIMER-BASED GLASS COMPOSITES WASHINGTON, UNIVERSITY OF (US) 2007-07-05 US disclosed
US-20070152198-A1 ELECTRO-OPTIC DENDRIMER-BASED GLASS COMPOSITES WASHINGTON, UNIVERSITY OF (US) 2007-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100152338-A1 NONLINEAR OPTICAL MATERIAL COMPOSITION AND METHOD OF MANUFACTURE C5, OR10J3, C1S GPR35 1508/4885MEN1 4278/4885PRNP 3461/4885
US-20260098206-A1 Nonlinear Optical Chromophores Containing Donors with Substituents Giving High Steric Hinderance, and Methods of Making and Using the Same NT5M, SCO2, ELOC GPR35 1104/4885MEN1 4229/4885PRNP 2911/4885
US-20260085189-A1 Chromophores with New Ring-Locked Donors that Increase r33 and Stability SCO2, FOXO3, CCNO GPR35 3731/4885MEN1 3919/4885PRNP 2559/4885
US-20100029953-A1 PHENYLTETRAENE-BASED NONLINEAR OPTICAL CHROMOPHORES PTGES, AADAT, PPOX GPR35 1367/4885MEN1 3626/4885PRNP 335/4885
US-20260093155-A1 Nonlinear Optical Chromophores with New Donors that Increase Refractive Index LEO1, SCO2, HCN1 GPR35 2327/4885MEN1 4230/4885PRNP 3673/4885
US-20260085236-A1 Chromophores with New Bridges that Increase Refractive Index HCN1, LBR, HCN2 GPR35 3398/4885MEN1 4396/4885PRNP 3160/4885
US-20090118521-A1 NANOENGINEERED ORGANIC NONLINEAR OPTICAL GLASSES EYA3, CDH1, EYA2 GPR35 4174/4885MEN1 384/4885PRNP 3075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.