Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.52 |
| ▸ | REN | P00797 | 10/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5225871 | 0.84 | KLK5 (0.57) | KLK5RENPSEN1PSEN2APH1B | |
| SCHEMBL5386298 | 0.81 | KLK5 (0.57) | KLK5RENATMKMT2A | |
| SCHEMBL5386289 | 0.81 | KLK5 (0.57) | KLK5RENATMKMT2A | |
| SCHEMBL5220702 | 0.81 | REN (0.58) | KLK5RENATM | |
| SCHEMBL30318981 | 0.81 | REN (0.58) | KLK5RENATM | |
| SCHEMBL5379396 | 0.80 | KLK5 (0.54) | KLK5RENPSEN1PSEN2APH1B | |
| SCHEMBL5379391 | 0.80 | KLK5 (0.54) | KLK5RENPSEN1PSEN2APH1B | |
| SCHEMBL5379400 | 0.80 | KLK5 (0.54) | KLK5RENPSEN1PSEN2APH1B | |
| SCHEMBL5222893 | 0.79 | KLK5 (0.59) | KLK5RENPSEN1PSEN2APH1B | |
| SCHEMBL6205577 | 0.79 | KLK5 (0.59) | KLK5RENPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107384-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-09-23 | — | — | WO | disclosed |