SCHEMBL7878030

SCHEMBL7878030

CCCO[Si](C)(OCCC)c1ccc(S(=O)(=O)N=[N+]=[N-])cc1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
CA12 O43570 1/20 0.32
CA7 P43166 1/20 0.32
BCL2L1 Q07817 2/20 0.30
BAK1 Q16611 2/20 0.30
CA5A P35218 1/20 0.30
CA5B Q9Y2D0 1/20 0.30
ALDH1A1 P00352 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7622816 0.92 TSHR (0.36) CA1CA2CA9CA12CA7
SCHEMBL7878015 0.89
SCHEMBL7628196 0.89 CA1 (0.33) CA1CA2CA9CA12CA7
SCHEMBL7631034 0.84
SCHEMBL7622409 0.81 F2 (0.32) CA1CA2CA9BCL2L1BAK1
SCHEMBL7877837 0.81 TSHR (0.38) CA1CA2CA9CA12CA7
SCHEMBL7630010 0.80 BCL2L1 (0.30) CA1CA2CA9CA12CA7
SCHEMBL14798412 0.77 TSHR (0.42) CA1CA2CA9CA12CA7
SCHEMBL7877836 0.77 ABCB1 (0.34) CA1CA2CA9CA12CA7
SCHEMBL14798576 0.77 CA2 (0.37) CA1CA2CA9BCL2L1BAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6331597-B1 Azidosilane-modified, moisture-curable polyolefin polymers, process for making, and articles obtained therefrom THE DOW CHEMICAL COMPANY 2001-12-18 US disclosed