Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7887009 | 0.88 | HTR1D (0.53) | HTR1DMAPTTMPRSS2SLC6A4USP30 | |
| SCHEMBL7887288 | 0.87 | HTR1D (0.60) | HTR1DGHSRMAPTTMPRSS2SLC6A4 | |
| SCHEMBL7886696 | 0.86 | MAPK14 (0.43) | HTR1DPDE4DGHSRMAPTTMPRSS2 | |
| SCHEMBL7885324 | 0.86 | HTR1D (0.42) | HTR1DPDE4DGHSRTMPRSS2SLC6A4 | |
| SCHEMBL7885332 | 0.83 | HTR1D (0.62) | HTR1DGHSRMAPTTMPRSS2SLC6A4 | |
| SCHEMBL7877945 | 0.80 | HTR1D (0.51) | HTR1DPDE4DGHSRMAPTSLC6A4 | |
| SCHEMBL7886690 | 0.80 | HTR1D (0.56) | HTR1DMAPTTMPRSS2SLC6A4HTR2A | |
| SCHEMBL7887345 | 0.79 | HTR1D (0.70) | HTR1DPDE4DGHSRMAPTSLC6A4 | |
| SCHEMBL7887044 | 0.76 | HTR6 (0.61) | HTR1DPDE4DGHSRMAPTALOX12 | |
| SCHEMBL7884344 | 0.76 | HTR6 (0.48) | HTR1DPDE4DGHSRMAPTHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098892-A1 | BIPHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000005225-A1 | BIPHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-03 | — | — | WO | disclosed |