Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.54 |
| ▸ | NPC1 | O15118 | 12/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24229205 | 0.84 | RAB9A (0.50) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24229165 | 0.84 | RAB9A (0.50) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24229219 | 0.83 | RAB9A (0.49) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31731985 | 0.77 | RAB9A (0.67) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL18898340 | 0.77 | ALDH1A1 (0.51) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL824375 | 0.75 | NPC1 (0.69) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29531707 | 0.75 | NPC1 (0.69) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6388826 | 0.74 | RAB9A (0.67) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL26626249 | 0.73 | NPC1 (0.62) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13325909 | 0.72 | RAB9A (0.83) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177572-B1 | 2-AMIDOPHENOL OR 2-AMIDOTHIOPHENOL IS COUPLED TO A SOLID PHASE SUPPORT THROUGH A LINKER GROUP, SUCH THAT A BENZOXAZOLE OR A BENZOTHIAZOLE IS FORMED | SEPRACOR, INC. | 2001-01-23 | — | — | US | disclosed |