⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9292144 | 1.00 | — | — | |
| SCHEMBL12973119 | 1.00 | — | — | |
| SCHEMBL6016743 | 0.92 | — | — | |
| SCHEMBL8463940 | 0.89 | TSHR (0.42) | — | |
| SCHEMBL28168681 | 0.89 | NAAA (0.36) | — | |
| SCHEMBL20076569 | 0.89 | TSHR (0.42) | — | |
| SCHEMBL27692867 | 0.89 | TSHR (0.42) | — | |
| SCHEMBL7915172 | 0.89 | TSHR (0.42) | — | |
| SCHEMBL7915170 | 0.89 | TSHR (0.42) | — | |
| SCHEMBL27744129 | 0.89 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5247009-A | Reacted with an imine and an acid halide, tires | NIPPON ZEON CO., LTD. (JP) | 1993-09-21 | — | — | US | claimed |
| US-4677153-A | REACTING WITH AN ACYL HALIDE AND | NIPPON ZEON CO., LTD. (JP) | 1987-06-30 | — | — | US | claimed |
| CN-113068887-A | Rubber coating safety glove and preparation method thereof | 浙江康隆达特种防护科技股份有限公司 | 2021-07-06 | — | — | CN | disclosed |
| CN-113068887-A | Rubber coating safety glove and preparation method thereof | 浙江康隆达特种防护科技股份有限公司 | 2021-07-06 | — | — | CN | disclosed |
| US-20100093785-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2010-04-15 | — | — | US | disclosed |
| US-20090270446-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-10-29 | — | — | US | disclosed |
| US-7576135-B2 | Diamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7365205-B2 | Cyclic diamine derivatives useful as agents for preventing and/or treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism; inhibit activated blood coagulation factor X | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-04-29 | — | — | US | disclosed |
| US-7342014-B2 | Diamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-03-11 | — | — | US | disclosed |
| US-20080015215-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-01-17 | — | — | US | disclosed |
| US-6323346-B1 | REACTING A DIAZOACETIC ACID DERIVATIVE OF THE FORMULA N.SUB.2 CHR.SUP.4 WITH A CARBONYL COMPOUND OF FORMULA R.SUP.1 R.SUP.2 C.DBD.O AND AN AMINO-GROUP-CONTAINING COMPOUND OF FORMULA R.SUP.3 NH.SUB.2 IN THE PRESENCE OF AN IRIDIUM COMPLEX | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2001-11-27 | — | — | US | disclosed |
| EP-0670302-B1 | N-acyloxylalkyl carboxylic acid amides and process for their preparation | BAYER AG (DE) | 1998-02-11 | — | — | EP | disclosed |
| US-5710279-A | REACTION OF IMINE AND ANHYDRIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5599940-A | CHEMICAL INTERMEDIATE FOR PREPERATION OF AGROCHEMICAL AND PHARMACEUTICAL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-04 | — | — | US | disclosed |
| EP-0670302-A1 | N-acyloxylalkyl carboxylic acid amide and process for their preparation | BAYER AG (DE) | 1995-09-06 | — | — | EP | disclosed |
| US-5312849-A | Modified diene polymer, carbon black | NIPPON ZEON CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| US-5247009-A | Reacted with an imine and an acid halide, tires | NIPPON ZEON CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0198294-B1 | METHOD FOR MODIFYING RUBBERS | NIPPON ZEON CO., LTD. (JP) | 1989-01-04 | — | — | EP | disclosed |
| US-4677153-A | REACTING WITH AN ACYL HALIDE AND | NIPPON ZEON CO., LTD. (JP) | 1987-06-30 | — | — | US | disclosed |
| EP-0198294-A1 | Method for modifying rubbers | NIPPON ZEON CO., LTD. (JP) | 1986-10-22 | — | — | EP | disclosed |