Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7886098 | 0.89 | PDCD1 (0.31) | PDCD1CD274 | |
| SCHEMBL7889139 | 0.85 | — | — | |
| SCHEMBL5067417 | 0.84 | PDCD1 (0.33) | PDCD1CD274 | |
| SCHEMBL7597789 | 0.83 | PDCD1 (0.30) | PDCD1CD274 | |
| SCHEMBL796298 | 0.82 | BCHE (0.31) | PDCD1CD274 | |
| SCHEMBL7935166 | 0.82 | PDCD1 (0.32) | PDCD1CD274 | |
| SCHEMBL7886955 | 0.81 | — | — | |
| SCHEMBL5352550 | 0.80 | PDCD1 (0.30) | PDCD1CD274 | |
| SCHEMBL7643714 | 0.77 | PDCD1 (0.32) | PDCD1CD274 | |
| SCHEMBL8830685 | 0.77 | PDCD1 (0.32) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177376-B1 | REACTING METALLOCENE WITH ORGANOLITHIUM COMPOUND AND GRIGNARD COMPOUND, ACTIVATION, CONTACTING WITH SUPPORT | TARGOR GMBH (DE) | 2001-01-23 | — | — | US | disclosed |