SCHEMBL7878271

SCHEMBL7878271

O=C(Br)C1CCC(C(=O)Br)CC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
HPGD P15428 1/20 0.33
PLG P00747 1/20 0.32
PLAT P00750 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
CHRNB2 P17787 2/20 0.31
CHRNA3 P32297 2/20 0.31
CHRNA4 P43681 2/20 0.31
CHRNB3 Q05901 1/20 0.31
CHRNA6 Q15825 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA7 P36544 1/20 0.31
GABRP O00591 1/20 0.30
GABRD O14764 1/20 0.30
GABRA1 P14867 1/20 0.30
TSHR P16473 1/20 0.30
GABRB1 P18505 1/20 0.30
GABRG2 P18507 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2959600 1.00
SCHEMBL9180234 0.86 ACE (0.34) CES2CES1HPGDCHRNB2CHRNA3
SCHEMBL6113163 0.86
SCHEMBL4957438 0.86
SCHEMBL9815391 0.85 EPHX1 (0.37) MAPT
SCHEMBL3238850 0.83
SCHEMBL1278207 0.83 PLG (0.39) PLGPLATLMNA
SCHEMBL11135891 0.79 PLG (0.64) PLGPLATLMNA
SCHEMBL7786834 0.74 CES2 (0.41) CES2CES1LMNAMAPTCHRNB2
SCHEMBL14722351 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9321017-B2 Gas-separation membrane NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) 2016-04-26 US disclosed
US-20150033945-A1 GAS-SEPARATION MEMBRANE NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) 2015-02-05 US disclosed
US-6168649-B1 THIN DISCRIMINATING LAYER SELECTED FROM THE GROUP CONSISTING OF POLYCARBONATE, POLYESTER, AND POLYESTERCARBONATE. MG GENERON, INC. 2001-01-02 US disclosed
EP-0316960-B1 GAS SEPARATION MEMBRANES FROM BISPHENOL AF POLYCARBONATES AND POLYESTERCARBONATES THE DOW CHEMICAL COMPANY (US) 1993-03-31 EP disclosed
EP-0244126-B1 TETRABROMO BISPHENOL BASED POLYESTERCARBONATE MEMBRANES AND METHOD OF USING THE DOW CHEMICAL COMPANY (US) 1992-05-13 EP disclosed
US-4874401-A Gas separation membranes from bisphenol AF polycarbonates and polyestercarbonates THE DOW CHEMICAL COMPANY (US) 1989-10-17 US disclosed
US-4840646-A SEPARATION OF OXYGEN FROM NITROGEN IN GAS MIXTURES THE DOW CHEMICAL COMPANY (US) 1989-06-20 US disclosed
EP-0316960-A2 Gas separation membranes from bisphenol af polycarbonates and polyestercarbonates THE DOW CHEMICAL COMPANY (US) 1989-05-24 EP disclosed
EP-0244126-A2 Tetrabromo bisphenol based polyestercarbonate membranes and method of using THE DOW CHEMICAL COMPANY (US) 1987-11-04 EP disclosed
EP-0017740-B1 PREPARATION OF POLY(ESTER CARBONATE) BY INTERFACIAL METHOD ALLIED CORPORATION (US) 1984-04-25 EP disclosed
US-4255556-A Preparation of poly(ester carbonate) by interfacial method ALLIED CHEMICAL CORPORATION (US) 1981-03-10 US disclosed
EP-0017740-A1 Preparation of poly(ester carbonate) by interfacial method ALLIED CORPORATION (US) 1980-10-29 EP disclosed