SCHEMBL7786834

SCHEMBL7786834

O=C(Br)C1CCCC(C(=O)Br)C1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
CHRNB2 P17787 2/20 0.37
CHRNA3 P32297 2/20 0.37
CHRNA4 P43681 2/20 0.37
CHRNB3 Q05901 2/20 0.37
CHRNA6 Q15825 2/20 0.37
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
KMT2A Q03164 2/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
TSHR P16473 3/20 0.33
NOS2 P35228 1/20 0.33
ALDH1A1 P00352 1/20 0.33
RECQL P46063 1/20 0.33
HSD11B1 P28845 4/20 0.31
MAPK1 P28482 1/20 0.31
SLC6A1 P30531 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9180234 0.88 ACE (0.34) CES2CES1CHRNB2CHRNA3CHRNA4
SCHEMBL4957438 0.88
SCHEMBL6113163 0.81
SCHEMBL29077837 0.81
SCHEMBL3238850 0.79
SCHEMBL7878271 0.74 CES2 (0.35) CES2CES1CHRNB2CHRNA3CHRNA4
SCHEMBL2959600 0.74
SCHEMBL890370 0.73 CES2 (0.43) CES2CES1CHRNB2CHRNA3CHRNA4
SCHEMBL13868097 0.73 ACE (0.48) CES2CES1SMN1; SMN2TSHRSLC6A1
SCHEMBL29844 0.73 ACE (0.48) CES2CES1SMN1; SMN2TSHRSLC6A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0017740-B1 PREPARATION OF POLY(ESTER CARBONATE) BY INTERFACIAL METHOD ALLIED CORPORATION (US) 1984-04-25 EP claimed
US-4255556-A Preparation of poly(ester carbonate) by interfacial method ALLIED CHEMICAL CORPORATION (US) 1981-03-10 US claimed
EP-0017740-A1 Preparation of poly(ester carbonate) by interfacial method ALLIED CORPORATION (US) 1980-10-29 EP claimed
US-9321017-B2 Gas-separation membrane NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) 2016-04-26 US disclosed
US-20150033945-A1 GAS-SEPARATION MEMBRANE NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) 2015-02-05 US disclosed
EP-1148934-A1 MEMBRANE FOR SEPARATION OF XENON FROM OXYGEN AND NITROGEN AND METHOD OF USING SAME MESSER GRIESHEIM GMBH (DE) 2001-10-31 EP disclosed
US-6168649-B1 THIN DISCRIMINATING LAYER SELECTED FROM THE GROUP CONSISTING OF POLYCARBONATE, POLYESTER, AND POLYESTERCARBONATE. MG GENERON, INC. 2001-01-02 US disclosed
WO-2000033949-A1 MEMBRANE FOR SEPARATION OF XENON FROM OXYGEN AND NITROGEN AND METHOD OF USING SAME MESSER GRIESHEIM GMBH (DE) 2000-06-15 WO disclosed
EP-0316960-B1 GAS SEPARATION MEMBRANES FROM BISPHENOL AF POLYCARBONATES AND POLYESTERCARBONATES THE DOW CHEMICAL COMPANY (US) 1993-03-31 EP disclosed
EP-0244126-B1 TETRABROMO BISPHENOL BASED POLYESTERCARBONATE MEMBRANES AND METHOD OF USING THE DOW CHEMICAL COMPANY (US) 1992-05-13 EP disclosed
US-4874401-A Gas separation membranes from bisphenol AF polycarbonates and polyestercarbonates THE DOW CHEMICAL COMPANY (US) 1989-10-17 US disclosed
US-4840646-A SEPARATION OF OXYGEN FROM NITROGEN IN GAS MIXTURES THE DOW CHEMICAL COMPANY (US) 1989-06-20 US disclosed
EP-0316960-A2 Gas separation membranes from bisphenol af polycarbonates and polyestercarbonates THE DOW CHEMICAL COMPANY (US) 1989-05-24 EP disclosed
EP-0244126-A2 Tetrabromo bisphenol based polyestercarbonate membranes and method of using THE DOW CHEMICAL COMPANY (US) 1987-11-04 EP disclosed
EP-0017740-B1 PREPARATION OF POLY(ESTER CARBONATE) BY INTERFACIAL METHOD ALLIED CORPORATION (US) 1984-04-25 EP disclosed
US-4255556-A Preparation of poly(ester carbonate) by interfacial method ALLIED CHEMICAL CORPORATION (US) 1981-03-10 US disclosed
EP-0017740-A1 Preparation of poly(ester carbonate) by interfacial method ALLIED CORPORATION (US) 1980-10-29 EP disclosed