Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700639 | 0.87 | ALDH1A1 (0.40) | SMN1; SMN2PREPALDH1A1CA12CA9 | |
| SCHEMBL7702052 | 0.83 | L3MBTL1 (0.38) | ALDH1A1CA12CA9CA1CA2 | |
| SCHEMBL7703505 | 0.83 | KDM4E (0.47) | SMN1; SMN2PREPALDH1A1CA12CA9 | |
| SCHEMBL7702054 | 0.83 | L3MBTL1 (0.38) | ALDH1A1CA12CA9CA1CA2 | |
| SCHEMBL7703504 | 0.83 | KDM4E (0.47) | SMN1; SMN2PREPALDH1A1CA12CA9 | |
| SCHEMBL7385304 | 0.83 | MAPT (0.39) | RAB9APREPALDH1A1CA12CA9 | |
| SCHEMBL7696668 | 0.82 | CA12 (0.48) | RAB9APREPALDH1A1CA12CA9 | |
| SCHEMBL7699846 | 0.82 | TSHR (0.46) | USP2SMN1; SMN2RAB9AALDH1A1CA12 | |
| SCHEMBL7386364 | 0.81 | CA12 (0.37) | PREPALDH1A1CA12CA9CA1 | |
| SCHEMBL7385154 | 0.81 | ALDH1A1 (0.43) | SMN1; SMN2RAB9APREPALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073650-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999055690-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-04 | — | — | WO | disclosed |