Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.38 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515151 | 0.92 | MAPT (0.53) | MAPTLMNAMAPK14NOTUMSIGMAR1 | |
| SCHEMBL1515252 | 0.86 | — | — | |
| SCHEMBL139458 | 0.72 | ALDH1A1 (0.44) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL447031 | 0.72 | ALDH1A1 (0.44) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL448510 | 0.72 | ALDH1A1 (0.44) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL9481812 | 0.72 | CYP2A6 (0.58) | MAPTLMNATP53NISCHKDM4E | |
| Hydrochloric Acid SCHEMBL27482920 | 0.70 | CHRNB4 (0.43) | MAPTLMNAGAAKDM4EALDH1A1 | |
| Biphenyl SCHEMBL29268822 | 0.70 | ALDH1A1 (0.50) | MAPTLMNANOTUMKDM4EALDH1A1 | |
| SCHEMBL9728 | 0.69 | MAPT (1.00) | MAPTLMNANOTUMGAADDAH1 | |
| SCHEMBL42579 | 0.69 | ALDH1A1 (0.47) | MAPTSIGMAR1ALDH1A1HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111377818-A | (meth) acrylate compound, polymer, resist material, and method for producing (meth) acrylate compound | 捷恩智株式会社 | 2020-07-07 | — | — | CN | claimed |
| US-5849764-A | Antagonists of gonadotropin releasing hormone | MERCK & CO., INC. (US) | 1998-12-15 | — | — | US | claimed |
| CN-111377818-A | (meth) acrylate compound, polymer, resist material, and method for producing (meth) acrylate compound | 捷恩智株式会社 | 2020-07-07 | — | — | CN | disclosed |
| WO-2001056358-A2 | ENHANCED PROPERTIED PESTICIDES | ROHM AND HAAS COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |
| US-5246914-A | Fungicides and plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-21 | — | — | US | disclosed |