Bromide

Bromide

SCHEMBL7878846

[Br-].[Br-].c1ccc2c(c1)-c1ccccc1C2[Zr+2]C1c2ccccc2-c2ccccc21

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 3/20 0.34
CHRM2 known ✓ P08172 1/20 0.34
CHRM1 known ✓ P11229 1/20 0.34
OPRM1 known ✓ P35372 1/20 0.34
GPR3 P46089 2/20 0.42
HTR2A P28223 2/20 0.42
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HDAC9 Q9UKV0 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37
NCOR2 Q9Y618 1/20 0.37
CYP1A2 P05177 2/20 0.35
POLB P06746 2/20 0.35
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35
BCHE P06276 2/20 0.34
HTR1A P08908 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride Ion SCHEMBL1131320 0.94 GPR3 (0.42) GPR3HTR2AHDAC3HDAC4HDAC7
Hydrochloric Acid SCHEMBL618216 0.94 GPR3 (0.42) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL8379078 0.94 GPR3 (0.42) GPR3HTR2AHDAC3HDAC4HDAC7
Hydrochloric Acid SCHEMBL8599251 0.92 GPR3 (0.41) GPR3HTR2AHDAC3HDAC4HDAC7
Hydrochloric Acid SCHEMBL8378993 0.92 GPR3 (0.41) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL8702175 0.90 GPR3 (0.44) GPR3HTR2AHDAC3HDAC4HDAC7
Ethylene SCHEMBL6914332 0.90 GPR3 (0.39) GPR3HTR2AHDAC3HDAC4HDAC7
Ethane SCHEMBL8163438 0.90 GPR3 (0.44) GPR3HTR2AHDAC3HDAC4HDAC7
Hydrochloric Acid SCHEMBL5355296 0.79 ELANE (0.42) GPR3CYP1A2KMT2AMEN1
Hydrochloric Acid SCHEMBL30724638 0.77 GPR3 (0.34) GPR3HTR2AHDAC3HDAC4HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10604604-B2 Multimodal polyolefin resin, and molded body manufactured therefrom DAELIM INDUSTRIAL CO., LTD. (KR) 2020-03-31 US disclosed
EP-3239196-B1 MULTIMODAL POLYOLEFIN RESIN HAVING HIGH MELT STRENGTH AND MOLDED PRODUCT PREPARED WITH THE SAME DAELIM IND CO LTD (KR) 2019-08-28 EP disclosed
US-20180305481-A1 MULTIMODAL POLYOLEFIN RESIN, AND MOLDED BODY MANUFACTURED THEREFROM DL CHEMICAL CO., LTD. (KR) 2018-10-25 US disclosed
EP-3369752-A1 MULTIMODAL POLYOLEFIN RESIN, AND MOLDED BODY MANUFACTURED THEREFROM Daelim Industrial Co., Ltd. (KR) 2018-09-05 EP disclosed
US-10040883-B2 Multimodal polyolefin resin and molded product prepared therefrom DAELIM INDUSTRIAL CO., LTD. (KR) 2018-08-07 US disclosed
US-9975977-B2 Multimodal polyolefin resin having high melt strength and molded product prepared with the same DAELIM INDUSTRIAL CO., LTD. (KR) 2018-05-22 US disclosed
EP-2832753-B1 MULTIMODAL POLYOLEFIN RESIN AND MOLDED PRODUCT PREPARED THEREFROM DAELIM IND CO LTD (KR) 2018-04-11 EP disclosed
EP-3239196-A1 MULTIMODAL POLYOLEFIN RESIN HAVING HIGH MELT STRENGTH AND MOLDED PRODUCT PREPARED WITH THE SAME Daelim Industrial Co., Ltd (KR) 2017-11-01 EP disclosed
US-20170306069-A1 MULTIMODAL POLYOLEFIN RESIN HAVING HIGH MELT STRENGTH AND MOLDED PRODUCT PREPARED WITH THE SAME DL CHEMICAL CO., LTD. (KR) 2017-10-26 US disclosed
EP-2832753-A1 MULTIMODAL POLYOLEFIN RESIN AND MOLDED PRODUCT PREPARED THEREFROM Daelim Industrial Co., Ltd. (KR) 2015-02-04 EP disclosed
US-6333388-B1 Aluminum compound-containing solid catalyst component, catalyst for olefin polymerization and method for producing olefin polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-12-25 US disclosed
US-6288193-B1 Ethylene-based polymer SUMITOMO CHEMICAL CO., LTD. (JP) 2001-09-11 US disclosed
US-6100213-A Aluminum compound-containing solid catalyst component, catalyst for olefin polymerization and method for producing olefin polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-08-08 US disclosed
EP-0767184-B1 Carrier for olefin polymerization catalyst, olefin polymerization catalyst and process for producing olefin polymer SUMITOMO CHEMICAL CO (JP) 1999-08-18 EP disclosed
US-5916982-A Process for the production of polyolefins NIPPON OIL CO., LTD. (JP) 1999-06-29 US disclosed
EP-0768320-A1 Catalyst component and catalyst NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed
EP-0768319-A1 Process for the production of polyolefins NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed
EP-0767184-A1 Carrier for olefin polymerization catalyst, olefin polymerization catalyst and process for producing olefin polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-04-09 EP disclosed