Hydrochloric Acid

Hydrochloric Acid

SCHEMBL8599251

[Cl-].[Cl-].[SiH4].c1ccc2c(c1)-c1ccccc1C2[Zr+2]C1c2ccccc2-c2ccccc21

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 3/20 0.33
CHRM2 known ✓ P08172 1/20 0.33
CHRM1 known ✓ P11229 1/20 0.33
SLC6A2 known ✓ P23975 1/20 0.33
SLC6A3 known ✓ Q01959 1/20 0.33
GPR3 P46089 2/20 0.41
HTR2A P28223 2/20 0.41
CYP19A1 P11511 1/20 0.36
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
NCOR2 Q9Y618 1/20 0.35
CYP1A2 P05177 2/20 0.34
POLB P06746 2/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL618216 0.97 GPR3 (0.42) GPR3HTR2ACYP19A1HDAC3HDAC4
Hydrochloric Acid SCHEMBL8378993 0.95 GPR3 (0.41) GPR3HTR2ACYP19A1HDAC3HDAC4
Ethane SCHEMBL8163438 0.92 GPR3 (0.44) GPR3HTR2ACYP19A1HDAC3HDAC4
Ethylene SCHEMBL6914332 0.92 GPR3 (0.39) GPR3HTR2ACYP19A1HDAC3HDAC4
Fluoride Ion SCHEMBL1131320 0.92 GPR3 (0.42) GPR3HTR2ACYP19A1HDAC3HDAC4
SCHEMBL8379078 0.92 GPR3 (0.42) GPR3HTR2ACYP19A1HDAC3HDAC4
Bromide SCHEMBL7878846 0.92 GPR3 (0.42) GPR3HTR2ACYP19A1HDAC3HDAC4
SCHEMBL8702175 0.87 GPR3 (0.44) GPR3HTR2ACYP19A1HDAC3HDAC4
Hydrochloric Acid SCHEMBL5355296 0.81 ELANE (0.42) GPR3CYP1A2KMT2AMEN1
Hydrochloric Acid SCHEMBL30724638 0.80 GPR3 (0.34) GPR3HTR2ACYP19A1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0822964-A1 MIXTURES OF BITUMEN AND OLEFIN POLYMERS SUITABLE FOR MODIFYING BITUMENS Montell North America Inc. (US) 1998-02-11 EP disclosed
WO-1997031065-A1 MIXTURES OF BITUMEN AND OLEFIN POLYMERS SUITABLE FOR MODIFYING BITUMENS MONTELL NORTH AMERICA INC. (IT) 1997-08-28 WO disclosed