Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.72 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.61 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.61 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.61 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.61 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.61 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.61 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.61 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29979393 | 0.84 | BRD4 (1.00) | BRD4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL248620 | 0.84 | BRD4 (1.00) | BRD4GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL30293227 | 0.82 | BRD4 (0.96) | BRD4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2428383 | 0.77 | GRIN2D (1.00) | BRD4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL15478601 | 0.74 | DAO (0.68) | BRD4KDM4EMEN1KMT2AGAA | |
| SCHEMBL28531473 | 0.74 | GRIN2D (0.57) | BRD4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16381141 | 0.74 | DAO (0.68) | BRD4GRM1KDM4EMEN1KMT2A | |
| SCHEMBL830151 | 0.74 | GRIN2D (0.57) | BRD4GRIN2DGRIN3BGRIN1GRIN2A | |
| Pyridine SCHEMBL11505122 | 0.74 | BRD4 (0.77) | BRD4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22198960 | 0.73 | GRIN2D (0.66) | BRD4GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329546-B1 | FOR INVESTIGATING THE MECHANISM OF ACTION OF A PHYSIOLOGICALLY ACTIVE AMINO ACID COMPOUND SUCH AS GLUTAMIC ACID IN AN ORGANISM | LABORATORY OF MOLECULAR BIOPHOTONICS (JP) | 2001-12-11 | — | — | US | disclosed |