Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 1.00 |
| ▸ | DAO | P14920 | 1/20 | 0.60 |
| ▸ | DDO | Q99489 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.56 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.54 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.54 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248620 | 1.00 | BRD4 (1.00) | BRD4DAODDOKDRCHEK1 | |
| Hydrochloric Acid SCHEMBL30293227 | 0.98 | BRD4 (0.96) | BRD4DAODDOKDRCHEK1 | |
| Pyridine SCHEMBL11505122 | 0.88 | BRD4 (0.77) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL7879101 | 0.84 | BRD4 (0.72) | BRD4DAODDOCHEK1GRIN2D | |
| SCHEMBL29206326 | 0.78 | BRD4 (0.64) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL16381141 | 0.78 | DAO (0.68) | BRD4DAODDOKDM4EALDH1A1 | |
| SCHEMBL15478601 | 0.78 | DAO (0.68) | BRD4DAODDOKDM4EALDH1A1 | |
| SCHEMBL1263927 | 0.76 | KDM4E (0.66) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL31154599 | 0.76 | KDM4E (0.66) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL31065667 | 0.76 | BRD4 (0.60) | BRD4KDM4EALDH1A1HPGDRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160237-A | Fluorescent probe for detecting hydrogen sulfide and preparation method and application thereof | 王威 | 2022-10-11 | — | — | CN | claimed |
| CN-116891456-A | Heterocyclic derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-115160237-A | Fluorescent probe for detecting hydrogen sulfide and preparation method and application thereof | 王威 | 2022-10-11 | — | — | CN | disclosed |