Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 20/20 | 0.67 |
| ▸ | CASP7 | P55210 | 15/20 | 0.67 |
| ▸ | CASP1 | P29466 | 8/20 | 0.67 |
| ▸ | CASP9 | P55211 | 6/20 | 0.67 |
| ▸ | CASP10 | Q92851 | 3/20 | 0.63 |
| ▸ | CASP4 | P49662 | 3/20 | 0.54 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.53 |
| ▸ | CASP5 | P51878 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7888146 | 0.90 | CASP3 (0.55) | CASP3CASP7CASP1CASP9CASP10 | |
| SCHEMBL9962302 | 0.88 | CASP3 (0.81) | CASP3CASP7CASP1CASP9CASP10 | |
| SCHEMBL3719465 | 0.88 | CASP3 (0.70) | CASP3CASP7CASP1CASP9CASP10 | |
| SCHEMBL7878192 | 0.82 | CASP3 (0.68) | CASP3CASP7CASP1CASP9CASP10 | |
| SCHEMBL29362585 | 0.82 | CASP3 (0.76) | CASP3CASP7CASP1CASP9CASP10 | |
| SCHEMBL20052414 | 0.81 | CASP3 (0.72) | CASP3CASP7CASP1CASP9CASP10 | |
| SCHEMBL15462663 | 0.81 | CASP3 (0.72) | CASP3CASP7CASP1CASP9CASP10 | |
| SCHEMBL20355928 | 0.81 | CASP3 (0.72) | CASP3CASP7CASP1CASP9CASP10 | |
| SCHEMBL17326941 | 0.81 | CASP3 (0.72) | CASP3CASP7CASP1CASP9CASP10 | |
| SCHEMBL7887169 | 0.80 | CASP3 (1.00) | CASP3CASP7CASP1CASP9CASP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010133000-A1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | NEW WORLD LABORATORIES INC. (CA) | 2010-11-25 | — | — | WO | disclosed |