Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PAM | P19021 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7880302 | 0.87 | SLC7A5 (0.51) | SLC7A5ALDH1A1GAAGFERKDM4E | |
| SCHEMBL7882515 | 0.87 | LOXL2 (0.51) | SLC7A5ALDH1A1GAAGFERKDM4E | |
| SCHEMBL31478027 | 0.86 | SLC7A5 (0.59) | SLC7A5ALDH1A1GAAGFERKDM4E | |
| SCHEMBL907660 | 0.86 | SLC7A5 (0.59) | SLC7A5ALDH1A1GAAGFERKDM4E | |
| Hydrochloric Acid SCHEMBL3949455 | 0.85 | SLC7A5 (0.57) | SLC7A5ALDH1A1GAAGFERKDM4E | |
| Hydrochloric Acid SCHEMBL6984256 | 0.85 | SLC7A5 (0.57) | SLC7A5ALDH1A1GAAGFERKDM4E | |
| SCHEMBL480042 | 0.83 | SLC7A5 (0.59) | SLC7A5ALDH1A1GAAGFERKDM4E | |
| SCHEMBL27499053 | 0.79 | ALDH1A1 (0.59) | SLC7A5ALDH1A1GAAGFERKDM4E | |
| SCHEMBL1870609 | 0.79 | ALDH1A1 (0.62) | SLC7A5ALDH1A1KDM4ELMNAHPGD | |
| Benzene SCHEMBL28096336 | 0.79 | ALDH1A1 (0.62) | SLC7A5ALDH1A1KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6333308-B1 | FOR THERAPY OF THROMBOSES, CARDIAC INFARCT, A CORONARY HEART DISORDER, ARTERIOSCLEROSIS, A TUMOR, OSTEOPOROSIS, AN INFLAMMATION OR AN INFECTION, OSTEOPOROSIS, AN INFLAMMATION OR AN INFECTION | MERCK KGAA (DE) | 2001-12-25 | — | — | US | disclosed |