SCHEMBL7879529

SCHEMBL7879529

CC=CC(=O)OCCC[SiH2]OC(CC)CCC

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.44
HCAR2 Q8TDS4 4/20 0.40
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TSHR P16473 2/20 0.35
HPGD P15428 1/20 0.35
APP P05067 5/20 0.32
GSTP1 P09211 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7876341 0.93 ATM (0.43) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL7880363 0.84 TSHR (0.54) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL7593092 0.81 ATM (0.42) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL8718828 0.78 ATM (0.50) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL7879592 0.77 TSHR (0.54) ATMHCAR2TSHRHPGD
SCHEMBL6550566 0.76 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL2427216 0.76 ATM (0.46) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL3954898 0.75 ATM (0.37) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4807492 0.75 ATM (0.37) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL22092322 0.73 ATM (0.50) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6331373-B1 CHARGE STABILITY AND FLUIDITY NIPPON SHOKUBAI CO., LTD. (JP) 2001-12-18 US disclosed