SCHEMBL787967

SCHEMBL787967

c1ccc2c(c1)sc1c(-c3ccc4[nH]c5ccc(-c6cccc7c6sc6ccccc67)cc5c4c3)cccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.64
MAPT P10636 4/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
RAB9A P51151 2/20 0.46
PRKDC P78527 3/20 0.44
PARP14 Q460N5 1/20 0.43
TNKS O95271 3/20 0.42
TNKS2 Q9H2K2 3/20 0.42
GPR3 P46089 2/20 0.39
AHR P35869 1/20 0.39
PIK3CD O00329 1/20 0.37
BRD4 O60885 1/20 0.37
PIK3CA P42336 1/20 0.37
PIK3CB P42338 1/20 0.37
MTOR P42345 1/20 0.37
PIK3CG P48736 1/20 0.37
KCNH2 Q12809 1/20 0.37
BRDT Q58F21 1/20 0.37
CDK4 P11802 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL457901 0.97 ALOX5 (0.61) ALOX5MAPTMEN1KMT2ARAB9A
SCHEMBL31664386 0.97 ALOX5 (0.61) ALOX5MAPTMEN1KMT2ARAB9A
SCHEMBL29720834 0.97 ALOX5 (0.61) ALOX5MAPTMEN1KMT2ARAB9A
SCHEMBL789548 0.94 ALOX5 (0.58) ALOX5MAPTMEN1KMT2ARAB9A
SCHEMBL10225922 0.94 ALOX5 (0.58) ALOX5MAPTMEN1KMT2ARAB9A
SCHEMBL10225928 0.94 ALOX5 (0.58) ALOX5MAPTMEN1KMT2ARAB9A
SCHEMBL26022356 0.94 ALOX5 (0.58) ALOX5MAPTMEN1KMT2ARAB9A
SCHEMBL10225924 0.93 ALOX5 (0.57) ALOX5MAPTMEN1KMT2ARAB9A
SCHEMBL10225921 0.93 ALOX5 (0.57) ALOX5MAPTMEN1KMT2ARAB9A
SCHEMBL789531 0.92 ALOX5 (0.56) ALOX5MAPTMEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018137-A1 COMPOUND, METHOD FOR PRODUCING SAME, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT MITSUBISHI CHEMICAL CORPORATION (JP) 2024-01-18 US disclosed
US-10727419-B2 Organic light emitting display device LG DISPLAY CO., LTD. (KR) 2020-07-28 US disclosed
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-20160133855-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO., LTD. (KR) 2016-05-12 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
WO-2012039262-A1 CARBAZOLE DERIVATIVE, LIGHT-EMITTING ELEMENT MATERIAL AND ORGANIC SEMICONDUCTOR MATERIAL SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-29 WO disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 ALOX5 1162/4885MAPT 1509/4885MEN1 3326/4885
US-20240018137-A1 COMPOUND, METHOD FOR PRODUCING SAME, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT F12, SEM1, NOX1 ALOX5 1044/4885MAPT 1254/4885MEN1 776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.