Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.52 |
| ▸ | CYP26A1 | O43174 | 8/20 | 0.52 |
| ▸ | RARG | P13631 | 8/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.52 |
| ▸ | RARA | P10276 | 7/20 | 0.52 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.52 |
| ▸ | CYP26B1 | Q9NR63 | 4/20 | 0.43 |
| ▸ | RXRA | P19793 | 5/20 | 0.42 |
| ▸ | RXRB | P28702 | 5/20 | 0.42 |
| ▸ | RXRG | P48443 | 3/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879749 | 0.85 | RARB (0.72) | RARBCYP26A1RARGCYP3A4RARA | |
| SCHEMBL8686334 | 0.76 | RARB (0.57) | RARBCYP26A1RARGCYP3A4RARA | |
| SCHEMBL7876436 | 0.76 | RXRA (0.48) | RARBCYP26A1RARGCYP3A4RARA | |
| SCHEMBL7876437 | 0.76 | RXRA (0.48) | RARBCYP26A1RARGCYP3A4RARA | |
| SCHEMBL7566725 | 0.73 | CYP3A4 (0.56) | RARBCYP26A1RARGCYP3A4RARA | |
| SCHEMBL7882967 | 0.71 | RARB (0.68) | RARBCYP26A1RARGCYP3A4RARA | |
| SCHEMBL9484975 | 0.71 | RARB (0.67) | RARBCYP26A1RARGCYP3A4RARA | |
| SCHEMBL7872264 | 0.70 | RARB (0.62) | RARBCYP26A1RARGCYP3A4RARA | |
| SCHEMBL7715323 | 0.70 | RARB (0.80) | RARBCYP26A1RARGCYP3A4RARA | |
| SCHEMBL7709220 | 0.70 | CYP3A4 (0.65) | RARBCYP26A1RARGCYP3A4RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326510-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-12-04 | — | — | US | disclosed |