Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.72 |
| ▸ | RARG | P13631 | 8/20 | 0.72 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.72 |
| ▸ | RARA | P10276 | 5/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.72 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.72 |
| ▸ | CYP26B1 | Q9NR63 | 4/20 | 0.59 |
| ▸ | RXRA | P19793 | 11/20 | 0.59 |
| ▸ | RXRB | P28702 | 9/20 | 0.59 |
| ▸ | RXRG | P48443 | 6/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879784 | 0.85 | RARB (0.52) | RARBRARGCYP26A1RARACYP3A4 | |
| SCHEMBL7715323 | 0.85 | RARB (0.80) | RARBRARGCYP26A1RARACYP3A4 | |
| SCHEMBL3302926 | 0.84 | RARB (1.00) | RARBRARGCYP26A1RARACYP3A4 | |
| SCHEMBL29353973 | 0.84 | RARB (1.00) | RARBRARGCYP26A1RARACYP3A4 | |
| SCHEMBL6373022 | 0.80 | RARB (0.75) | RARBRARGCYP26A1RARACYP3A4 | |
| SCHEMBL7882967 | 0.79 | RARB (0.68) | RARBRARGCYP26A1RARACYP3A4 | |
| SCHEMBL8686334 | 0.78 | RARB (0.57) | RARBRARGCYP26A1RARACYP3A4 | |
| SCHEMBL9165893 | 0.78 | RXRA (0.69) | RARBRARGCYP26A1RARACYP3A4 | |
| SCHEMBL6881850 | 0.78 | RARB (0.71) | RARBRARGCYP26A1RARACYP3A4 | |
| SCHEMBL7746407 | 0.78 | RARB (0.76) | RARBRARGCYP26A1RARACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326510-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-12-04 | — | — | US | claimed |
| US-6326510-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-12-04 | — | — | US | disclosed |
| US-5942586-A | Catalyst for the polymerization of olefins, process for its preparation and its use | TARGOR GMBH (DE) | 1999-08-24 | — | — | US | disclosed |
| EP-0901462-A1 | BI-AROMATIC COMPOUNDS, COMPOSITIONS CONTAINING THEM AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1999-03-17 | — | — | EP | disclosed |
| WO-1998034909-A1 | BI-AROMATIC COMPOUNDS, COMPOSITIONS CONTAINING THEM AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-08-13 | — | — | WO | disclosed |