Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 5/20 | 0.62 |
| ▸ | RARA | P10276 | 5/20 | 0.62 |
| ▸ | RARB | P10826 | 4/20 | 0.62 |
| ▸ | RXRA | P19793 | 15/20 | 0.56 |
| ▸ | RXRB | P28702 | 9/20 | 0.51 |
| ▸ | RXRG | P48443 | 9/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879838 | 1.00 | RARG (0.62) | RARGRARARARBRXRARXRB | |
| SCHEMBL7878427 | 0.86 | RARG (0.57) | RARGRARARARBRXRARXRB | |
| SCHEMBL7878425 | 0.86 | RARG (0.57) | RARGRARARARBRXRARXRB | |
| SCHEMBL8189489 | 0.83 | RARG (0.54) | RARGRARARARBRXRARXRB | |
| SCHEMBL8189493 | 0.83 | RARG (0.54) | RARGRARARARBRXRARXRB | |
| SCHEMBL7879827 | 0.81 | RARG (0.52) | RARGRARARARBRXRARXRB | |
| SCHEMBL7879831 | 0.81 | RARG (0.52) | RARGRARARARBRXRARXRB | |
| SCHEMBL7761215 | 0.79 | RXRA (0.52) | RARGRARARARBRXRARXRB | |
| SCHEMBL7761270 | 0.79 | RXRA (0.52) | RARGRARARARBRXRARXRB | |
| SCHEMBL6876422 | 0.78 | RXRA (0.66) | RARGRARARARBRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326510-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-12-04 | — | — | US | disclosed |
| EP-0901462-A1 | BI-AROMATIC COMPOUNDS, COMPOSITIONS CONTAINING THEM AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1999-03-17 | — | — | EP | disclosed |
| WO-1998034909-A1 | BI-AROMATIC COMPOUNDS, COMPOSITIONS CONTAINING THEM AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-08-13 | — | — | WO | disclosed |