⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13159800 | 0.77 | ALOX15 (0.32) | — | |
| SCHEMBL26440490 | 0.68 | — | — | |
| SCHEMBL12656252 | 0.67 | — | — | |
| SCHEMBL24966711 | 0.66 | — | — | |
| SCHEMBL10188219 | 0.62 | — | — | |
| SCHEMBL18072487 | 0.57 | — | — | |
| SCHEMBL13159696 | 0.54 | — | — | |
| SCHEMBL12807999 | 0.54 | — | — | |
| SCHEMBL14282889 | 0.54 | — | — | |
| SCHEMBL10081411 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139747-A1 | 1H-IMIDAZO[4, 5-c]QUINOLINONE COMPOUNDS, USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2010-12-09 | — | — | WO | disclosed |