⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23616914 | 0.78 | — | — | |
| SCHEMBL12656252 | 0.78 | — | — | |
| SCHEMBL16090092 | 0.73 | TSHR (0.31) | — | |
| SCHEMBL13159800 | 0.72 | ALOX15 (0.32) | — | |
| SCHEMBL1684896 | 0.72 | — | — | |
| SCHEMBL7171889 | 0.69 | — | — | |
| SCHEMBL16090801 | 0.69 | — | — | |
| SCHEMBL25070160 | 0.69 | ALDH1A1 (0.30) | — | |
| SCHEMBL16455137 | 0.69 | — | — | |
| SCHEMBL29086880 | 0.68 | THRB (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807638-B2 | 5- and 6-azaindole compounds for inhibition of Bcr-Abl tyrosine kinases | ENLIVEN INC. (US) | 2023-11-07 | — | — | US | disclosed |
| US-20230130724-A1 | 5- AND 6-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES | ENLIVEN INC. | 2023-04-27 | — | — | US | disclosed |