Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LHCGR | P22888 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7885708 | 0.91 | HHAT (0.56) | ALDH1A1MAPK1HHATNPSR1TP53 | |
| SCHEMBL7885990 | 0.87 | NPSR1 (0.51) | ALDH1A1MAPK1HHATNPSR1LHCGR | |
| SCHEMBL7888339 | 0.87 | MAPK1 (0.60) | MAPK1MAPTHHATNPSR1LHCGR | |
| SCHEMBL7887663 | 0.87 | CA12 (0.48) | ALDH1A1MAPK1MAPTHHATNPSR1 | |
| SCHEMBL8171464 | 0.86 | HHAT (0.51) | MAPK1HHATNPSR1TP53POLB | |
| SCHEMBL8171470 | 0.86 | HHAT (0.51) | ALDH1A1MAPK1HHATNPSR1TP53 | |
| SCHEMBL7892023 | 0.86 | MAPK1 (0.61) | MAPK1HHATNPSR1LHCGR | |
| SCHEMBL7891831 | 0.86 | HHAT (0.65) | ALDH1A1MAPK1HHATNPSR1TP53 | |
| SCHEMBL7889885 | 0.84 | POLB (0.61) | MAPK1HHATNPSR1POLBLHCGR | |
| SCHEMBL7889806 | 0.84 | LHCGR (0.53) | MAPK1HHATNPSR1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177443-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2001-01-23 | — | — | US | disclosed |
| EP-0973778-A1 | 4,5,6,7-TETRAHYDRO-THIENO 3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998040385-A1 | 4,5,6,7-TETRAHYDRO-THIENO[3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-09-17 | — | — | WO | disclosed |