Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | LHCGR | P22888 | 11/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7887722 | 0.90 | MAPK1 (0.72) | MAPK1NPSR1LHCGRCA12CA1 | |
| SCHEMBL7887663 | 0.90 | CA12 (0.48) | MAPK1NPSR1LHCGRCA12CA1 | |
| SCHEMBL7885990 | 0.90 | NPSR1 (0.51) | MAPK1NPSR1LHCGRCA12CA1 | |
| SCHEMBL8226033 | 0.89 | LHCGR (0.59) | MAPK1NPSR1LHCGRCA12CA1 | |
| SCHEMBL7880254 | 0.87 | ALDH1A1 (0.60) | MAPK1NPSR1LHCGRHHATLMNA | |
| SCHEMBL7887404 | 0.86 | MAPK1 (0.66) | MAPK1NPSR1LHCGRCA12CA1 | |
| SCHEMBL7888302 | 0.85 | MAPK1 (0.65) | MAPK1NPSR1LHCGRHHAT | |
| SCHEMBL7885827 | 0.85 | LHCGR (0.67) | MAPK1NPSR1LHCGRHHAT | |
| SCHEMBL7885900 | 0.85 | LHCGR (0.71) | MAPK1NPSR1LHCGRHHAT | |
| SCHEMBL7880517 | 0.84 | MAPK1 (0.53) | MAPK1NPSR1LHCGRHHAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177443-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2001-01-23 | — | — | US | disclosed |
| EP-0973778-A1 | 4,5,6,7-TETRAHYDRO-THIENO 3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998040385-A1 | 4,5,6,7-TETRAHYDRO-THIENO[3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-09-17 | — | — | WO | disclosed |