Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 8/20 | 0.40 |
| ▸ | RAB9A | P51151 | 8/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14062970 | 0.89 | TDP1 (0.56) | TDP1ALDH1A1TP53TSHRMAPT | |
| SCHEMBL14063133 | 0.88 | TDP1 (0.54) | TDP1ALDH1A1TP53TSHRMAPT | |
| SCHEMBL14062670 | 0.86 | ALDH1A1 (0.58) | TDP1ALDH1A1TP53TSHRMAPT | |
| SCHEMBL14063128 | 0.82 | TDP1 (0.49) | TDP1ALDH1A1TP53TSHRMAPT | |
| SCHEMBL23868693 | 0.82 | TDP1 (0.59) | TDP1ALDH1A1TP53TSHRMAPT | |
| SCHEMBL2449724 | 0.82 | TDP1 (0.59) | TDP1ALDH1A1TP53TSHRMAPT | |
| SCHEMBL14063139 | 0.81 | ALDH1A1 (0.46) | TDP1ALDH1A1TP53TSHRMAPT | |
| SCHEMBL2446420 | 0.80 | TDP1 (0.66) | TDP1ALDH1A1TP53TSHRMAPT | |
| SCHEMBL2720991 | 0.80 | TDP1 (0.70) | TDP1ALDH1A1TP53TSHRMAPT | |
| SCHEMBL21202704 | 0.80 | TDP1 (0.70) | TDP1ALDH1A1TP53TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618914-B1 | OXIRANYL METHYL ETHERS EXHIBITING CHIRALITY, AND THEIR USE AS DOPANTS IN LIQUID-CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2001-10-17 | — | — | EP | disclosed |
| EP-0618914-A1 | OXIRANYL METHYL ETHERS EXHIBITING CHIRALITY, AND THEIR USE AS DOPANTS IN LIQUID-CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993013093-A1 | OXIRANYL METHYL ETHERS EXHIBITING CHIRALITY, AND THEIR USE AS DOPANTS IN LIQUID-CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |